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Biomedical subjects

D M Stoll

Publications and source records attributed to D M Stoll.

7 recordsLinked to original sources
PubMed1988

Human urinary epidermal growth factor excretion: age, sex, and race dependence.

We measured the urinary excretion of immunoreactive epidermal growth factor (IR-EGF) in random urine specimens obtained from 358 ambulatory patients and normal subjects, aged 18-90 yr, with a homologous EGF RIA. We also measured IR-EGF excretion in 24-h urine collections from 40 additional normal subjects, aged either 20-29 or 60-69 yr, to detect possible artifacts introduced in the analysis of random urine specimens by the age-related decline in the glomerular filtration rate. Urinary IR-EGF excretion decreased in a linear fashion with increasing age. Women excreted more IR-EGF than men, and whites excreted more IR-EGF than blacks of the same age and sex, but the rate of decline with increasing age was similar for all groups. These findings may provide additional insight into the role of EGF in human renal physiology.

Adult↗
PubMed1984

Association of bullous pemphigoid with systemic lupus erythematosus.

Seven previous cases of coexistent bullous pemphigoid (BP) and systemic lupus erythematosus (SLE) have been reported. An 83-year-old man had clinical, laboratory, and histologic evidence of both BP and SLE. The question of whether coexistent SLE and BP actually occur can be settled only when complete studies are available.

Adolescent↗
PubMed1983

Treatment of cutaneous pseudolymphoma with hydroxychloroquine.

A 45-year-old woman with generalized cutaneous pseudolymphoma of Spiegler-Fendt was successfully treated with hydroxychloroquine. It is felt that the suppression of lymphocyte and/or histiocyte function was responsible for the remission of the disease. This is apparently the first report of cutaneous pseudolymphoma of Spiegler-Fendt being successfully treated with antimalarials. The differentiation between cutaneous pseudolymphoma and cutaneous malignant lymphoma is also discussed.

Diagnosis, Differential↗
PubMed1980

Subungual keratoacanthoma.

Only 12 cases of lesions reputed to be subungual keratoacanthomas have been reported to our knowledge, and those have not been unequivocal by histologic and biologic criteria. Those 12 lesions have been tabulated by us and reviewed critically. In addition, we now provide two cases of keratoacanthomas in the subungual region that are histologically typical of keratoacanthomas found on hair-bearing skin. It appears to us that subungual keratoacanthoma is a specific type of keratoacanthoma that differs from the common solitary keratoacanthoma on hair bearing skin by 1) its similarity to verruca vulgaris clinically; 2) having more dyskeratotic cells and fewer neutrophils and eosinophils histologically; 3) being more vertical in orientation (longer than it is broad); 4) its failure to regress spontaneously; 5) its longer course; and 6) its tendency to destroy bone. Paradoxically, keratoacanthoma situated in the subungual region is a more destructive neoplasm than a squamous cell carcinoma there.

Adult↗