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D Mangar

Publications and source records attributed to D Mangar.

46 records · Page 3Linked to original sources
PubMed1991

High-performance liquid chromatography as a diagnostic tool in prolonged neuromuscular blockade.

We report the use of high-performance liquid chromatography (HPLC) to identify the cause of prolonged neuromuscular blockade in a child who had received 2 mg.kg-1 of succinylcholine. Upon analysis by HPLC the syringe was found to contain succinylcholine (10 mg.ml-1) and also atracurium (5 mg.ml-1), so that a diagnosis was established. In situations where medication errors are suspected, we recommend saving syringe contents for analysis for confirmation of the agent.

Anesthesia, Intravenous↗
PubMed1991

Serum levels of Hyskon during hysteroscopic procedures.

Hyskon hysteroscopy fluid is used with the hysteroscope as an aid in distending the uterine cavity and in visualizing its surfaces. We correlated the amount of Hyskon used during hysteroscopy with both the instillation pressures generated within the uterine cavity and with serum levels of Hyskon in 11 healthy subjects. Serum levels in excess of 1000 mg% were measured at 30 min when an amount of Hyskon greater than 300 mL was used. Intrauterine Hyskon absorption and/or injection during hysteroscopy were found even after volumes of Hyskon as small as 50-100 mL were used. Serum levels were significantly higher with the larger amounts of Hyskon used in ablative procedures (P less than 0.01), as compared with serum levels seen with the smaller amounts of Hyskon used for diagnostic procedures. The injection pressures should be low to minimize the amount of intravascular injection. In cases in which extensive ablative procedures are necessary, we suggest that a two-stage procedure be considered. Because of the hypertonicity of Hyskon, intravascular volume expansion that may be larger than that seen during transurethral prostatectomy occurs.

Absorption↗
PubMedDate not supplied

False negative transesophageal echocardiography in a patient with severe mitral regurgitation.

We present a patient with severe mitral regurgitation, diagnosed by cardiac catheterization and physical examination but not seen on transesophageal echocardiography (TEE) after general anesthesia. Subsequently, transthoracic echocardiography was performed with the regurgitant jet visualized. This case illustrates one of the limitations of TEE secondary to the use of a biplane probe. The availability and routine use of an omniplane probe may prevent this limitation. A complement of physical examination, imaging, and diagnostic tools, as well as thorough understanding of the limitations of each technique, is essential.

Aged↗