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Biomedical subjects

D Matthes

Publications and source records attributed to D Matthes.

16 recordsLinked to original sources

[Diagnosis of peripheral arterial occlusive disease: clinical, haemodynamic and metabolic investigation (author's transl)].

The value of quantitative (venous-occlusion plethysmography), semiquantitative (ultrasound-Doppler method; walking distance; duration of bicycle ergometry) and metabolic (lactate, pyruvate) tests was assessed in 41 patients with arterial occlusive disease of the upper leg type. It was demonstrated that blood pressure measurement using the Doppler method is of great importance. Significant differentiation between normal and impaired blood flow was obtained with venous-occulsion plethysmography for both "first flow" and "peak flow". The diagnostic value as to the degree of peripheral arterial disease was similar for plethysmography and Doppler methods. Duration of bicycle ergometry provided an important pointer to the degree of functional impairment of the affected extremity. The level of lactate and pyruvate in femoral venous blood is suitable more for serial controls and assessment of treatment in patients in whom haemodynamic studies have already clarified the diagnosis of impaired blood flow.

Adult↗

Spiroergometric and telemetric investigations during the XXI International Stoke Mandeville Games 1972 in Heidelberg.

Spiroergometric and telemetric investigations were carried out on 100 paralysed athletes during the XXI International Stoke Mandeville Games in Heidelberg, 1972. The technical and organisational difficulties in carrying out these measurements were engendered by the disabilities of subjects. The maximum oxygen uptake observed and the oxygen pulse were lower than in non-disabled persons. There were no differences in the peak heart rates (180-200 beats/min.) as compared with non-disabled athletes during particular competition situations. Sports characterised by quickness, dexterity and strength are not able to train the cardiopulomnary system substantially. Swimming is recommended as beneficial. Psychological and training physiological considerations suggest that long-distance wheelchair races should be adopted as a Stoke Mandeville event.

Adult↗

[Coronary-angiographic demonstration of the dilating effect of dipyridamole on coronary arteries and its inhibition by caffeine (author's transl)].

Selective coronary cineangiographies are performed repeatedly in 13 mongrel dogs. The contrast medium itself has no demonstrable dilating effect upon the vessels. After the first injection of 0.2 mg/kg of dipyridamole the left anterior coronary artery is significantly (p less than 0.001) dilated, which is in contrast to some results described in literature. Immediately after an injection of high doses of caffeine (10 mg/kg) the previously enlarged coronary diameter decreases significantly (p less than 0.001). During the action of caffeine subsequent infections of dipyridamole result in a very small, or no change in coronary diameter. The coronary-dilating effect of dipyridamole can be inhibited by high doses of caffeine (10 mg/kg).

Angiocardiography↗