Biomedical subjects

D Mazza

Publications and source records attributed to D Mazza.

At least 19 recordsLinked to original sources

PubMed2001

[Adenocarcinoma of the common bile duct and celiac disease].

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Adenocarcinoma↗

PubMed2000

What can we do about domestic violence?

Domestic violence is a complex issue at both an individual and public health level. Barriers to disclosure often lie with the doctor rather than the victim. Assessment of risk and devising a safety plan are important steps for the doctor to undertake with the victim. Recommendations for joint counselling or marriage guidance for the couple are usually not appropriate. The efficacy of population screening for domestic violence has not yet been demonstrated. More limited opportunistic screening is recommended, especially in the emergency department, mental health and obstetric settings, and general practice. Health professionals can be a bridge to resources within the community, but this requires knowledge of and liaison with those services.

Adult↗

PubMed2000

Clinical practice guidelines and the computer on your desk.

The majority of Australia's general practitioners are now believed to be using a computer to support clinical practice. This technology has the potential to deliver evidence-based clinical practice guidelines to the GP during consultations. If clinical practice guidelines are to be incorporated into electronic medical record systems, to assist clinical decision making at the point of care, guideline development will need to be significantly revised. Computerised clinical decision support at the time of consultation may become a major method for continuing medical education for Australian GPs.

Australia↗

PubMed2000

Specialized spring design in segmented edgewise orthodontics: further verification of dedicated software.

A software program for use in the investigation of specialized springs used in the segmented arch technique has previously been developed and an example of its clinical application has been shown. The purpose of this study was to further assess the reliability of the software in 4 tests using T-loop springs. A numerical simulation of a determined experimental condition relative to a T-loop spring was carried out in each test. Numerical and experimental results were compared, and the precision of the analytical tool was assessed relative to a variety of parameters of the spring. Since the comparison between numerical and experimental results showed good agreement along the entire range of activation of the spring, the reliability of the software is sufficient for the clinical purposes of the segmented arch technique.

Computer Simulation↗

PubMed2000

Measurement of T-cell-derived antigen binding molecules and immunoglobulin G specific to Candida albicans mannan in sera of patients with recurrent vulvovaginal candidiasis.

Immunoglobulin G (IgG) and T-cell-derived antigen binding molecules (TABM) specific to whole Candida extract and to Candida-derived mannans prepared by both the cetryltrimethylammonium bromide (CTAB) and alkaline degradation (PEAT) methods were measured in the sera of women with vulvovaginal candidiasis and controls. In the patients there were significantly higher levels of IgG to both CTAB and PEAT mannans and of TABM to CTAB mannan. TABM specific to CTAB mannan was purified from the serum of a patient with a high titer of this TABM. The purified TABM bound specifically to CTAB mannan and to other yeast and mold extracts. This TABM preparation was associated with transforming growth factor beta2 (TGF-beta2), and on specific binding to mannan there was a marked increase in the level of detectable TGF-beta2. This increase in TGF-beta2 level was critically dependent on the relative concentrations of the purified TABM and mannan, being smallest when either was in excess. The TABM specific to CTAB mannan was also shown to inhibit Candida-stimulated gamma interferon production. The results suggest that CTAB mannan-specific TABM may increase susceptibility to vulvovaginal candidiasis in association with a shift in the immune response to the Th2 type.

Adult↗

PubMed2000

Are part timers real GPs? Attitudes of general practitioners toward those who work part time.

BACKGROUND: Current attitudes within the medical profession suggest that one cannot be a 'real' doctor unless one works full time. The aim of this study was to determine the views and attitudes of a sample of GPs toward part time practice. METHOD: As part of a larger study, GPs in two divisions in metropolitan Melbourne were sent a questionnaire based survey. GPs were asked to rate statements about part time practice using a Likert scale. RESULTS: The response rate was 55% (n = 246). The majority of GPs disagreed with the statement 'part time GPs are not real GPs' but feelings were mixed about whether part timers covered the same range of clinical content as full timers. One fifth of respondents questioned the competence of part time GPs. Male GPs, those over 55 years and full timers were more likely to hold negative views toward part time general practice. DISCUSSION: Our results show a 'generational' pattern toward part time practice. With the increasing numbers of women entering general practice, these attitudes will need to change to accommodate the fact that more GPs will be choosing to work part time in the future.

Adult↗

PubMed2000

Laparoscopic removal of intragastric foreign bodies.

Ingestion of foreign bodies is a common happening for prison inmates. When such bodies do not pass, endoscopic or surgical retrieval is necessary. The authors report the case of a young patient in whom endoscopy failed to retrieve several intragastric foreign bodies. He was treated successfully by laparoscopic gastrotomy. The authors think that this approach is a valid alternative to laparotomy.

Adult↗

PubMed1999

Gastrointestinal mucormycosis and liver transplantation; a case report and review of the literature.

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Adult↗

PubMed1999

Liver transplantation and HBsAg-positive postnecrotic cirrhosis: adequate immunoprophylaxis and delta virus co-infection as the significant determinants of long-term prognosis.

BACKGROUND/AIMS: The place of liver transplantation in hepatitis B viral (HBV)-related diseases remains controversial because of the high rate of reinfection. The aim of this study was to define the determinants of long-term prognosis after transplantation. METHODS: Fifty-eight patients were transplanted during the period February 1984-September 1996. Six patients died during the early (< 3 months) posttransplant period from causes unrelated to HBV infection. All 52 long-term (> 3 months) survivors were evaluated in relation to the mode of presentation, viral replication at time of transplantation, absence of hepatocellular cancer at time of transplantation and use of adequate immunoprophylaxis (IP). Adequate immunoprophylaxis, defined as maintenance of anti-HBs levels over 100 mUI/ml, was introduced in December 1989. Intention-to-treat IP analysis compared patients transplanted before and after this date. The median follow-up was 74 months (range 4 to 131). Forty-seven patients (90%) had a minimal follow-up of 3 years. RESULTS: Five-year actuarial survival rates of 58 patients and of 52 long-term survivors were 72 +/- 6% and 80 +/- 6%, respectively. Univariate analysis showed that delta co-infection (n = 25) significantly improved survival (p < 0.001) [96 +/- 4% vs 63 +/- 10% in HBV patients (n = 27) at 5 years] as did absence of hepatocellular cancer (n = 36) (p = 0.020) [89 +/- 5% vs 61 +/- 12% in 16 non-cancer patients]. IP, however, significantly influenced 5-year survival in the HBV-patient group (n = 17) (p = 0.001) [85 +/- 10% vs 30 +/- 14% in 10 patients without IP). Multivariate analysis selected delta co-infection (p = 0.002) and IP (p = 0.01) as the significant determinants of prognosis independently influencing survival. Uni- and multivariate analyses showed that survival without reinfection was significantly influenced by IP (p = 0.002) [73 +/- 8% (n = 31) versus 33 +/- 12% in 15 non-treated patients). CONCLUSIONS: Delta virus co-infection and immunoprophylaxis are the most important prognostic factors after transplantation for postnecrotic HBsAg-positive cirrhosis. Transplantation can be proposed as a therapeutic tool only if life-long adequate adjuvant therapy can be achieved. Under this condition good results can even be obtained if there is viral replication at the time of transplantation.

Actuarial Analysis↗

PubMed1999