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Biomedical subjects

D Metzel

Publications and source records attributed to D Metzel.

8 recordsLinked to original sources
PubMed1988

[Current resistance status of pathogens isolated from bile and its development since 1976 in the Suhl district].

Bile was collected intraoperatively and through duodenal tubes from patients and was microbiologically investigated. E. coli and coliform bacteria were found to be the most common germs in bile, accounting for 51.6 per cent of all positive findings. Streptococcus faecalis and Proteus spec. increased remarkably to 17 per cent each. Calculated antibiotic therapy was found to depend for good success on knowledge of the latest resistance rates of the most common germs. These were 67 per cent E. coli to ampicillin and 40 per cent for E. coli to tetracycline and 53 or 91 per cent for Str. faecalis or Proteus spec. to tetracycline. Hence, these preparations will have to be abandoned for calculated therapy, say, for cholangitis.

Anti-Bacterial Agents↗
PubMed1986

[Current status and the development of resistance of important urinary pathogens to antibiotics in the Suhl district 1970-1984].

In a retrospective study over a period from 1970 to 1984 the distribution of frequency and the behaviour of the resistance of urine germs out of more than 43,000 sendings from outpatient and hospital institutions of the county of Suhl were analysed. In the period of observation the proportion of isolated E. coli redoubled and was nearly 68% in 1984. Conspicuous were a decrease of the isolates of Str. faecalis from 32 to 4% and an increase of problem germs of the Klebsiella group to 9.7%. The resistance situation is characterized by a distinct decrease of the resistance of E. coli in comparison to antimicrobial substances with smaller consumption (sulphonamides, chloramphenicol, nitrafurantoin) without homogeneous behaviour of the problem germs.

Anti-Bacterial Agents↗
PubMed1986

[Current resistance in surgical infections and its development since 1970].

More than 7,000 bacteriological samples were received by the authors and were analysed for the frequency of resistance among pyogenic cocci which are relevant to surgical practice. Staphylococcus aureus accounted for 41 per cent and Escherichia coli for 15.3 per cent. These were the most common germs in 1984. Resistance of Staphylococcus aureus to ampicillin was as high as 78 per cent. Resistance levels below eight per cent were recorded in the context of lincomycin, erythromycin, gentamicin, oxacillin, and berlocombin. Resistance ratios of Escherichia coli were 55.2 per cent to ampicillin, 4.5 per cent to gentamicin, and 12.6 per cent to berlocombin.

Abscess↗
PubMed1975

[Possibilities of chemical germ-conservation and its meaning for the bacteriological urine diagnosis].

To estimate the germ-preserving effect of 15 percent disodium-calcium-ethylene-diamine-tetraacetate, 1.8 percent boric acid, 20 percent dimethyl sulfoxide and 3 solutions containing 0.001 percent merthiolate and 15 percent glycerin, 2 percent ethylene-diamine-tetraacetic acid and 15 percent glycerin, and 30 percent NaCl and 3 percent polyvinyl pyrrolidone respectively, comparative investigations were conducted in 4 series comprising a total of 400 urine samples. Boric acid, which is very easy to use, proved the most effective. After 24-h storage at room temperature of boric-acid-preserved urine samples with bacterial counts of over 10-4 per ml, the results were false-negative in 2-4 percent; after 48 h the rate was 6-8 percent and after 72 h nearly 10 percent. There were no false-positive results.

Bacteriological Techniques↗