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Biomedical subjects

D Meyniel

Publications and source records attributed to D Meyniel.

36 records · Page 2Linked to original sources
PubMed1982

[Hepatic tuberculosis: anatomical and clinical findings. A review of forty-six cases (author's transl)].

Over eight years the authors recorded 46 cases of hepatic tuberculosis. Most cases occurred in patients from black Africa. Forty-five patients had at least one extrahepatic tuberculous localization. Moderate cholestasis, without jaundice, found in 75% of patients, was the main biologic disorder. Upon histologic examination, five different types of granulomas were found. Each one has a specific predictive value concerning the outcome of the tuberculous infection.

Adult↗
PubMed1982

[Colic carcinoma and basal cell epithelioma eleven years after Kaposi sarcoma with splenic and cutaneous involvement (author's transl)].

A case of Kaposi sarcoma (KS) with cutaneous and splenic involvement is reported. Carcinoma of the left colon and basal cell epithelioma arose eleven years after KS. Genetic, viral, and immunologic factors which may promote initiation and development of Kaposi sarcoma are reviewed. The responsibility of immunodeficiency, whether resulting from therapy or from other causes, in carcinogenesis is discussed. Prolonged survival may be seen after KS. Another primary malignant disease (lymphoma or solid tumor) may arise. The authors suggest that the risk of immunologic disorders, occurring spontaneously or induced by therapy, should be considered specifically for each patient with KS.

Adenocarcinoma↗
PubMed1982

[Primary reticulum-cell sarcoma (Parker-Jackson sarcoma) of the rib. Report of a case with a five-year survival after surgery, radiation therapy and chemotherapy (author's transl)].

A case of primary reticulum-cell sarcoma of the rib is reported. This rare tumor arose in an unusual site and was revealed by an exceptional clinical picture. Extensive hemothorax was the initial manifestation. Follow-up exceeds five years. Prognosis is not as poor for reticulum-cell sarcoma as for Ewing sarcoma. After radical surgery, radiation therapy and chemotherapy, the five-year total remission rate approximates 50%.

Adult↗
PubMed1982

[Two cases of pentastomiasis observed in Paris (author's transl)].

The observations of two black African patients seen among 940 hospitalized patients are reported. Intraabdominal calcified larvas, probably of Porocephalus (Armillifer) armillatus were found in both patients. The cycle of this Pentostomida is recalled. Attention is drawn to the role of snake slime in accidental contamination of human beings. In man, this parasitic infection is almost always asymptomatic and detected fortuitously on roentgenograms, or during surgery or necropsy.

Adult↗
PubMed1981

[Vitamin B12 deficiency in chronic atrophic gastritis. 3 cases (author's transl)].

The megaloblastic anaemia observed in patients with chronic atrophic gastritis is usually due to malabsorption of vitamin B12. In some cases, the absence of intrinsic factor supports the diagnosis of pernicious anaemia but other factors, the importance of which varies from case to case, are also involved. They include proliferation of bacteria in the lumen of the gut, intestinal cell abnormalities resulting from lack of vitamin B12 and low hydrochloric acid output with subsequent reduction in the release of vitamin B12 from foodstuffs. With regard to treatment, it would seem justified to combine oral broad-spectrum antibiotics with parenteral administration of vitamin B12.

Achlorhydria↗
PubMed1980

[Fever, hepatic granulomatosis, electrocardiogram changes, and a positive serodiagnosis for Yersinia enterocolitica: two case reports (author's transl)].

Though no bacteria were isolated, a diagnosis of Yersinia enterocolitica infection was confirmed in two patients by strongly positive serology tests, with levels much above the normal. Both patients had fever, hepatic granulomatosis, and electrocardiogram anomalies, and there was associated dysuria and prostatitis in one case. The authors review the hepatic, urinary, and electrocardiogram manifestations reported in the published literature, and describe the antigenic and serologic relationships existing between Y. enterocolitica type 9 and Brucella abortus.

Adult↗
PubMed1979

[Cholestatic hepatitis during treatment with I.N.H. and rifampicin: arguments in favour of the hepatotoxicity of rifampicin (author's transl)].

It is generally accepted that hepatitis occurring during treatment with INH and rifampicine results from the hepatotoxicity of INH metabolites. A case is reported of cholestatic hepatitis occurring during such treatment, in which there was a previous history of an isolated hepatic affection. The administration of INH and rifampicin caused cholestasis alone, which reoccurred after rifampicin administration only. No immuno-allergic phenomenon has been shown to be involved in rifampicin toxicity. This observation suggests that rifampicin may be hepatotoxic itself, especially in patients with previous hepatic affections.

Aged↗
PubMed1977

[Criteria of identification of schistosomiasis caused by Schistosoma hamatobium and S. mansoni (486 patients: 275 case of schistosomiasis)].

Out of a total of 486 patients who originated from French Equatorial Africa, from the West Indies or from the Indian Ocean, the authors identified 275 cases of schistosomiasis of which 230 were due to S. Hematobium and 45 to S. Mansoni. The diagnostic methods were biopsy of the rectal mucosa, immunofluorescence, in the West Indians, examination of the stools, in the Africans examination of the urine, intravenous urography and less often cystoscopy. The value of these investigations was studied in each case, then by comparison with one another and with data in the literature. The most valuable investigation was biopsy of the rectum, better in Africans than examination of the urine, immunofluorescence and better than cystoscopy when this was possible.

Adolescent↗
PubMed1976

[Pulmonary, pleural and pericardial manifestations of rickettsiosis].

The authors report four observations of rickettsioses with R. conori (3 cases) or R. mooseri (1 case) with pericardial, pleural or pulmonary manifestations (2 cases). On this occasion, they recall that diagnosis of rickettsiosis can only be made on precise conditions: compatible clinical syndrome, significantly increasing then decreasing antibodies level, negative bacteriological and viral investigations and effectiveness of particular antibiotics. They also recall the main characteristics of pericardites, pleurisies, and pneumopathies produced by rickettsiae, probably more frequently than previously thought.

Adult↗
PubMedDate not supplied

[One hundred and twenty-three cases of sickle-cell trait (author's transl)].

One hundred and twenty-three cases of sickle-cell trait (122 negro immigrants) are studied in a department of internal medicine. The frequencies of G6PD deficiency, anemia, splenomegaly and tuberculosis are neighbouring at the negro without hemoglobinopathy. The relationship between the sickle-cell trait and the reason of admission of the final diagnosis il likely in 2,4 % of the cases, doubtfully in 15,4 %, null in the other cases. The occasional (hemolytic, thrombotic, painful, visceral, osseous) manifestations of the sickle-cell trait (apart from the constant hyposthenuria) and their mechanism are summarized and discussed.

Africa↗