[Therapeutics and arterial aging. Antiaggregants].
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Biomedical subjects
Publications and source records attributed to D Midy.
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An atypical evolution of the mandibular cartilage was recorded in systematic dissections of the neck in the Anatomy Laboratory. This anomaly led to the formation of a supernumerary bony fragment in the concavity of the lower edge of the mandibular arch, with a slight adhesion thereto. This observation is reported by the authors after a recapitulation of the embryology.
An exact study was made of the middle nasal meatus in 20 anatomical preparations (left and right) from 10 subjects. Some features (the ethmoidal bulla, the uncinate process of the ethmoidal bone, the openings of the maxillary and frontal sinuses) are relatively constant in their arrangement, but very variable in shape and size. An understanding of these structures is now essential for the practice of endonasal microsurgery.
100 dissections performed in the Anatomy Laboratory have made it possible to clarify certain details relating to the cervical trajectory of the accessory nerve (traditionally called the 11th or spinal nerve), its relationship with the jugular vein, with the S.C.M. muscle, its position on the anterior and posterior edges of the S.C.M. and on the anterior edge of the trapezius muscle, and the frequency of its branching in the sub-clavicular fossa.
The authors report the observation of a paraprosthetic fistula revealed by three episodes of digestive haemorrhage, illustrating the diagnostic and therapeutic difficulties brought about by the erosion of the duodenum by a sub-renal aortic prosthesis. A review of the literature confirms the rarity and the gravity of this pathology, and underlines the per-operative preventive measures.
A new artificial connective matrix which results from two reactions of fibrinogen and fibronectin on elastin was used to obturate a slit made in the abdominal aorta of rabbit. The so-called Elastin-Fibrin biomaterial behaved as a scaffold through which all the different structures were restored to their former condition. At 3 months, the material had disappeared and no thrombus, no inflammation or reject had been detected.
The anatomy of the accessory n. is defined in the light of 100 dissections with particular regard to the following aspects: its relations with the internal jugular v.; its participation in the innervation of the sternocleidomastoid m.; its location in relation to the anterior and posterior borders of that muscle and to the anterior border of the trapezius; and its branching and anastomoses in the supraclavicular fossa.
Protein coating and endothelial cell preseeding have been proposed and studied as improvements to arterial prostheses. In this paper, an impervious polyester vascular graft which had been coated with cross-linked gelatin was compared to a porous one over a period of up to 8 months in dogs. This evaluation involved in vivo methods using radio tracers to study patency and thrombogenicity and in vitro controls of the healing processes. The main advantages offered by coated grafts over uncoated include the absence of preclotting and better biointegration.
A serie of 20 dissections carried out in the anatomy Laboratory enabled us to make a close observation of the middle meatus of the nasal cavity. Certain anatomical parts such as the bulla, the unciform process, the ostia of the maxillary and frontal sinus are relatively set in their positions, but quite variable in their shape and size. This knowledge is now indispensable, at a time when endonasal microsurgery has become commonplace in ENT.
The authors report their experience of thin wall PTFE IMPRA prostheses in providing vascular access for chronic haemodialysis. Sixty-six prostheses were inserted between 14/10/1983 and 31/10/1986, with review of all patients at 31/6/1987. Twenty-three per cent of patients died during the study period. Patency analysed by the actuarial method was 49.07 +/- 15.7% at 2 years. There was no evidence of any significant difference between use of the forearm and of the arm. The main cause of failure was early (responsible for the loss of 9.2% of prostheses) or secondary (after the first month) thrombosis. A total of 30.3% of prostheses were lost by thrombosis by the end of 2 years, the principal cause being anastomotic or post-anastomotic venous stenosis. The use of thin walls in no way modified the incidence of this complication. The authors suggest its preventive protection by routine ansography. False aneurysms occurred beyond 18 months of dialysis requiring removal of the prosthesis in 3 cases. Thinning of the wall is one of the probable factors involved in this complications, justifying the abandonment of this type of prosthesis in this indication despite technical advantages at implantation and during use.
Studies of the fascio-cutaneous vascularization and innervation of the leg seem incomplete. After reviewing the classical findings, the authors report on their anatomic study 15 dissections. Perforating pedicles, originating from the peroneal artery (3 to 5) and posterior tibial artery (4 to 5) destined for the skin and fascia of the posterior aspect of the leg were constantly found. This study suggests the possibility of a distally based sural fascio-cutaneous flap, a flap which has been successfully constructed clinically.
In 200 dissections of internal jugular veins, the valves were investigated with regard to their constitution, their macroscopic and their microscopic anatomy. In 88% of the cases, an ostial valve was found. The cusp of each consists of two parts in 77%, of only one part in 16%, and in 7% of three parts. In 12% these valves are not found. The structure, the configuration, the topography of these valves are explained. The stroma of the valve consists of collagen and elastic fibrils. The surface of the luminal and parietal part is covered by endothelial cells with elastic and muscular fibers close to the attachment of the cusp to the vein wall.
Very many painful syndromes of the forefoot remain without a satisfactory explanation; although this region contains quite specific structures, it has suffered from the application of analogies with disorders of the hand. Among these specific components, the presence of the supra-transverse intermetatarsocapital bursa provides an explanation of such clinical entities as the acute syndrome of the second intermetatarsal space and gives fresh impetus to the debate on the etiopathogenesis of Morton's metatarsalgia. On the basis of 25 dissections, the authors studied the region between the metatarsal heads, confirming the presence of these bursae and specifying their site and size and particularly their relations with the common plantar digital nerve at its bifurcation into collateral nerves.
The authors present the results of dissection of 40 facial arteries and their collaterals. The study of the collaterals is specifically for the cervical portion of this artery and especially for the three segments of its facial portion. The artery and its collaterals are extremely variable as regards its mode of termination. 4 types of artery are presented: labial, angular, nasal and abortive. The global description of the vascularization of the face and the principal anastomoses leads on to a study of the facial flaps and the plastic surgery of the face.
A series of 80 dissections was performed to define the anastomoses between the cervical plexus and the hypoglossal nerve (XII), the superior anastomosis between the trunk of XII and the ansa of the atlas from the cervical plexus; the ansa cervicalis, traditionally known as the ansa of the XIIth cranial nerve or hypoglossal ansa, formed by the direct junctional anastomosis of the descending branch of XII and the internal descending branch of the cervical plexus. The origins, form, branches and chief relations are defined in in the present study.
About twenty five dissections of the forefoot, we have precised the presence of serosis burses, upper the profound transversal intermetatarsus ligament, in the intercapito metatarsus region. These burses, recently described by Bossley (New Zealand), are not described in the classical anatomic books. Variable in the first and forth spaces, they are always present in the second and third spaces, where their very anterior situation realizes a privileged connexion with the digital nerve, at its division. In precising the situation and the anatomic characteristics of these burses, this study contributes to clarify the etiology of some inflammatory or static pains of the foot.
This paper begins with a review of the embryology of the inguinal region. The authors then point out the special morphological and topographical features of the inguinal canal in male children. These observations were based on the study of 50 inguinal canals from male children. From the anatomical observations described in this study guidelines are proposed for the surgical approach and dissection of the spermatic cord used in the treatment of congenital hernias or abnormal descent of the testis.
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