Biomedical subjects
Publications and source records attributed to D Migliore.
Wax D(P), a peptido-glycolipid found in extracts of Mycobacterium tuberculosis var. hominis, was not found in extracts of three strains of still-grown M. tuberculosis var. bovis (BCG, Marmorek and Dupray). However, extracts from three other bovine strains (Behring, LA and BB) did yield waxes D(P), and these did not differ as to their molar ratios of alanine/glutamic acid/diaminopimelic acid from human waxes D(P).
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Delipidated human casein was digested with trypsin and the enzymatic digest was fractionated on Sephadex G-50. The peptidic fractions were assayed for immunomodulating activity in two in vitro models. Fractions corresponding to molecular weights in the range of 2,000 +/- 600 were found to possess stimulating activity in these models.