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Biomedical subjects

D Mihăilescu

Publications and source records attributed to D Mihăilescu.

13 recordsLinked to original sources

[Renal ectopia].

Explore the source record for details and available documents.

Adult

Specific protection against bovine leukemia virus infection conferred on cattle by the Romanian inactivated vaccine BL-VACC-RO.

The Romanian BL-VACC-RO vaccine against bovine leukemia virus (BLV) infection was prepared with ethylenimine-inactivated BLV obtained from persistently infected cell lines. Intramuscular administration of two vaccine doses (each containing 0.40 mg virus glycoprotein with adjuvant), 2 weeks apart, conferred protection against challenge infection with BLV on 18 of the 20 vaccinated calves. Two calves were not protected, in spite of their positive serologic response to vaccination. The results demonstrate the efficiency of the BL-VACC-RO vaccine in preventing BLV infection.

Animals

Investigations of the presence of serum antibodies to Epstein-Barr virus in patients with various tumors.

Serum samples from 150 patients with various malignant or benign tumors and from 20 clinically healthy subjects were tested by indirect immunofluorescence (IF) reaction for the presence of specific antibodies to Epstein-Barr-virus-determined viral capsid antigen (EB VCA). The IF test-carried out in multitest-slide EB3 and Raji cell preparations-revealed antibodies to EB VCA in 102 of the patients with tumors and in 4 of the healthy persons.

Antibodies, Viral