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D Milicic

Publications and source records attributed to D Milicic.

5 recordsLinked to original sources

A tinnitus objectivization: how we do it.

The medical therapy of tinnitus should be oriented by objective measurement of the disorder. Preferably, it should be qualitative, indicating the exact neural mechanism to be neuromodulated by neuroprotective medication. The neurophysiological approach in objectivization of tinnitus is presented by means of auditory brainstem response and middle latency response. These tests could be applied in functional follow-up of medical therapy, as these are more sensitive and harmless methods as compared to standard morphological methods.

Adult↗

Nutritional influences on growth and prevalence of anaemia in children during the war in Sarajevo.

OBJECTIVE: To assess growth and prevalence of anaemia in hospitalised children during the war in Sarajevo. DESIGN: A random sample of children who were patients in the paediatric clinic over a period of six months (1 June to 31 December 1993) were anthropometrically measured and blood samples taken to determine prevalence of anaemia. SETTING: The study was conducted at the paediatric clinic, Kosevo Hospital, Sarajevo. SUBJECTS: The sample comprised 542 children aged from 0 to 14 years of whom 50.6% were boys and 49.4% were girls. INTERVENTIONS: The children were weighed and had their heights measured. Nutritional status was assessed through calculating the weight for height percentile and comparing these with international standards. Blood samples were taken and low haematocrit and haemoglobin values were used to indicate nutritional anaemia. The cut-off points used were: haematocrit < 0.34 (6 months-5 years) and < 0.35 (6-14 years); haemoglobin < 105 g/l (6 months-5 years) and < 110 g/l (6-14 years). RESULTS: On average, 69% of boys and 71% of girls fell within the 10th to 90th percentile range (weight for height). 7% of boys and 5% of girls were below the 5th percentile. A total of 24.7% children aged from six months to five years and 16% of children aged from six to 14 years had haematocrit values below the cut-off points. The highest percentage of children with low haematocrit values came from the six months to one year age group. Anaemia as defined by haemoglobin value was diagnosed in 10.6% of children aged from six months to five years and 9.6% of six to 14 year olds. CONCLUSIONS: War and disruption of the food supply have not had the expected negative impact of child growth and prevalence of anaemia. Reasons for this may include: increased levels of breast feeding, distribution of supplementary food commodities enriched with micronutrients, and good parental care.

Adolescent↗

[Differences in serum selenium concentration in probands and patients with colorectal neoplasms in Zagreb, Croatia].

Serum selenium concentration (scSe) (microgram/l) was comparatively measured in healthy persons (n = 202), patients with colorectal adenoma(s) (n = 44) and colorectal carcinoma (n = 48). In patients with adenoma(s) scSe (59.05 +/- 15) was significantly lower (p < 0.001) compared with scSe in the control group (66.8 +/- 14.43). Hyposelenemia was more pronounced in patients with multiple polyps (n = 11) than in patients with single adenoma (n = 33) (p < 0.05). Patients with colorectal carcinoma had also significant decrease in scSe (50.93 +/- 13.81) compared with the control group (p < 0.001 and with the adenoma patients (p < 0.001). According to the analysis of variance, highly significant differences were found among the cancer patients stratified in Dukes' stages A to D (p < 0.001), indicating a strong negative correlation between extension of cancer and hyposelenemia. Furthermore, hyposelenemia seemed to be more pronounced in the mucinous type of carcinoma than in adenocarcinoma (p = 0.056). This results indicate that hyposelenemia is strongly associated with colorectal neoplasia (including extension and severity of the disease) and that it may not only be a result but also one of tumorogenic factors. That means that selenium supplementation could be important in prevention or even adjuvant therapy of colorectal cancer.

Adenomatous Polyposis Coli↗