During a 3-year period, nine girls and two boys (age range, 2 days-13 years) with congenital choanal atresia were evaluated by computed tomography (CT). Other associated congenital anomalies, primarily craniofacial anomalies, were present in six of the 11 patients. In six patients the atresia was bilateral and consisted of both bony and membranous components. Of the five patients with unilateral atresia, the lesions were on the right in three and on the left in two. CT demonstrated the atresia, choanal stenosis, septal deviation, and thickening of the vomer and palatine bone. The ease of CT examination and the high accuracy of the results make it the preferred imaging method for evaluating choanal atresia.

Adolescent↗

PubMedDate not supplied

[Male hypogonadotrophic hypogonadism: successful treatment of infertility with HMG + HCG (author's transl)].

Ten typical cases of male eunuchoidism (two with anosmia) are reported. After administration of clomifene citrate to five patients there was no change in blood levels of gonadotrophins in four cases; in the fifth, a small and transitory increase of LH was noted. The intravenous injection of LHRH (100 mcg) to five patients induced an increase of serum LH in all cases and serum FSH in three cases. The initial site of the dysfunction is possibly hypothalamic with secondary gonadotrophic pituitary insufficiency. Among six patients desiring paternity, prolonged treatment (for 36 to 98 weeks), with HCG(1700-7000 I.U. weekly) + HMG (450-825 I.U. FSG weekly) resulted in the appearance of spermatozoa in the seminal fluid in five cases and a pregnancy was obtained in four cases. Methods of treatment are discussed.

Adult↗