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Biomedical subjects

D Milosević

Publications and source records attributed to D Milosević.

At least 19 recordsLinked to original sources

[Giant osteomas of the paranasal sinuses].

At the Otorhinolaryngologic Department in Novi Sad we investigated osteomas of the paranasal cavities registered from 1960 to 1989. The total number of the treated patients was 30, aged from 31 to 60 years. A special attention is given to a female patient, aged 65 years with osteoma covering two thirds of the right nostril, both ethmoids and right retrobulbar space. It progressed upwards to the base of the skull causing denudation of the dura mater at the surface of 2.5 x 1.5 cm, and consecutive liquorrhea. The removed tumor weighed 110 grams and belonged to giant osteomas of the paranasal cavities.

Adolescent

[Determination of T lymphocyte subpopulations in malignant lymphoproliferative diseases].

The aim of this work was to investigate T cell subset composition of peripheral blood cells in patients with acute myeloid leukaemia, acute lymphoblastic and chronic lymphocytic leukaemia, by enumerating T cells positive for receptors for sheep erythrocytes (E-RFC, A-RFC) using the method of E-rosette, and for CD3, CD4 and CD8 antigens, by indirect immunofluorescence technique, using the monoclonal antibodies of the OK series. The study was performed on 57 patients without therapy and 46 healthy persons. The results of enumeration of T cells and their subsets obtained in the stage of the disease when the total leukocyte count was below 20 x 10(9)/L, were markedly decreased in all three types of leukaemias. The most significant decrease of relative count of T cells and their subpopulations was obtained in CLL patients. Analysis of T cells subsets and their ratio in CLL patient in the stage of disease when the total leukocyte count as higher than 20 x 10(9)/L, demonstrated the most pronounced decrease of total T lymphocytes and CD4+ cells. The relative count of the "active" (A-RFC)T cells and CD8+ cells did not change, and was the same as in the patients suffering from CLL with a lower leukocyte count.

Humans

Potentiation of experimental allergic thyroiditis in rats adipectomized at birth.

The effect of neonatal extirpation of the interscapular brown adipose tissue (adipectomy) on the development of experimental allergic thyroiditis in 8-week-old inbred Lewis rats was studied. The incidence and intensity of disease were much higher, and delayed skin reactions significantly stronger, in adipectomized rats than in control sham-adipectomized rats.

Adipose Tissue