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Biomedical subjects

D Moschinski

Publications and source records attributed to D Moschinski.

At least 19 recordsLinked to original sources
PubMed1993

[Rehabilitation of fresh, surgically managed anteromedial knee instabilities].

In between 1983 and 1988, 33 patients suffering from an acute antero-medial instability of the knee were operated on for the anterior cruciate ligament. The reconstruction of the ligament was performed by transcondylar fixation. 25 of these patients took part in a retrospective examination. The postoperative treatment had been carried out according to various concepts of rehabilitation. Our investigations were supposed to measure the restoration of the muscular efficiency of the knee-extensor and -flexor by isokinetic training arrangements. The results revealed that by the operation a sufficient stabilization of the knee had not been achieved. 18 of 25 patients once more showed an antero-medial instability of the knee. Twelve of these 25 patients had an extended anterior instability. Only in seven cases the muscular system was completely restored with average isokinetic muscle efficiency. The high rate of postoperative knee-instability proves the persistent sports-incapacity. We must draw the conclusion that the after-treatment of ligamentous injuries about the knee must focus on the muscular rehabilitation.

Adult↗
PubMed1983

[Osteosynthesis of distal lower leg fractures].

Unfavorable stability relationships in the case of distal lower leg bone fractures after tibiaosteosynthesis can lead to late postoperative complications such as the formation of pseudarthroses or a breaking of the metal plate. A possibility of decreasing the extent of these complications is provided by the simultaneous supply of osteosynthesis to both the tibia and fibula. For this purpose three individual cases were presented. Other results were discussed.

Adolescent↗
PubMed1982

[Isolated varicosis of the small intestine (without portal hypertension) causing massive upper gastrointestinal bleeding (author's transl)].

A case report is given of a 24 year old patient who had relapsing massive gastrointestinal bleeding from varices in the duodenum and jejunum, due to occlusion of the mesenterial vein. There is only one similar case described in the literature. 97 patients with varices of the small intestine have been described; in 41 of these cases there was extrahepatic, in 47 intrahepatic portal hypertension. In 60 of the 91 cases varices were found in the duodenum, less frequently in the ileum or jejunum too. In another 10 cases varices had formed around an ileostomy. In 1/3 of all cases abdominal surgery had preceded formation of varices in the small intestine. Pathogenesis, diagnosis and therapy are discussed.

Adult↗
PubMed1980

The influence of zinc on bone healing in rats.

The importance and necessity of the trace element zinc for tissue restitution after injuries has been known for a long time. The influence of zinc on the healing of tibial fractures in rats is studied by daily administration of 0.6 mg zinc-dl-aspartate compared to a non-treated control group. There is a significant decrease of bone-zinc concentration after fracture. This decrease can be balanced out by zinc administration. There are no significant alterations in serum levels of zinc in both groups. Fracture healing is not affected. Zinc accumulates in bones.

Animals↗
PubMed1980

[The trace-element zinc in medial fractures of the collum femoris and in coxarthrosis (author's transl)].

In a comparative study among two groups of patients--persons with a medial fracture of the collum femoris and persons with advanced coxarthrosis--the zinc-content of the femur was measured. For this analysis a bone-biopsy was performed when an endoprothesis was implanted. In some of the patients the zinc-levels in the blood were determined on several occasions. If the zinc-content of the blood was low, similarly the zinc-content of the bone was reduced, especially in patients with medial fractures. In patients with severe coxarthrosis the zinc-content is reduced by 50%.

Aged↗
PubMed1980

Hepatic production of VLDL-triglycerides. Dependence of portal substrate and insulin concentration.

Insulin has an exacerbating effect on endogenous hypertriglyceridemia. Experiments were carried out in order to study the acute effects of insulin in 6 patients with endogenous hypertriglyceridemia and 6 controls. 0.1 Unit insulin/kg body weight was injected into the portal vein. Blood samples were taken from the portal and hepatic veins and analysed for FFA, glycerol, VLDL-triglycerides (VLDL-TG) and insulin. Liver blood flow was measured with cardiogreen. This technique allowed a study of the acute effect of insulin on the hepatic extraction of substrates and on the hepatic production of VLDL-TG. Under basal conditions the production of VLDL-TG in patients with endogenous hypertriglyceridemia was not statistically different from the production in controls. The results did not provide statistical proof of a correlation between the production and the hepatic uptake of VLDL-TG precursors; however, the production was negatively correlated to the hepatic clearance rate of insulin. During a one-hour observation period after the application of insulin, the production of VLDL-TG was decreased in controls and increased in patients with endogenous hypertriglyceridemia. The application of insulin was also followed by a decreased uptake of free fatty acids and glycerol, this change being similar in controls and in patients with endogenous hypertriglyceridemia. There was no correlation between the effect of insulin on the production of VLDL-TG and on the uptake of substrates by the liver. It is concluded that insulin has a direct effect on the production of VLDL-TG which is independent of substrate supply. The adverse effect of insulin in endogenous hypertriglyceridemia may reflect some type of impaired hepatic responsiveness to insulin.

Adult↗
PubMed1977

[The treatment to the high gastric ulcer (author's transl)].

This is a report on 64 patients, who were operated on because of gastric ulcer situated near the cardia. We found the best results after the so-called step-like resection, which is preferable to selective vagotomy with excision of the ulcer and pyloroplasty because of the special conditions of the secretion of gastric juice in the case of high ulcers. Because of the danger of the development of a cancer in a B-II-stomach we prefer the B-I-anastomosis. For ulcers with stenosis of the esophagus a cardiofundectomy should be performed. Ulcers high on the greater curvature and in the fundus should be excised and a distal gastrectomy (B-I) should follow. The sole excision of the ulcer or the operation according to Kelling-Madlener are not recommended.

Adult↗
PubMed1977

[Ulcerocancer of the stomach (author's transl)].

46 patients were operated upon for an ulcerocancer of the stomach. In detail the differential diagnosis and the possibilities for preoperatively establishing an exact diagnosis are described. The good results after resection of the tumor (5-year-survival rates are for early cancer 100% and for the other tumors 67.7%) demonstrate, that usually for the ulcerocancer a total gastrectomy is unnecessary. Depending on the localisation of the tumor a proximal or distal resection of the stomach is sufficient. The results indicate that tumors, in which the ulcer floor shows a partial infiltration of carcinomatous cells, are not to be called as ulcerocancer. It is suggested to speak of these cases of "primary" carcinoma of the stomach.

Adult↗
PubMed1975

[The penetrating duodenal ulcer. Operative technique and postoperative complications (author's transl)].

The results of 133 gastric resections for penetrating duodenal ulcer are reported. Because of the postoperative complications (acute hemorrhagic pancreatitis, duodenal stump insufficiency, icterus and intraluminal postoperative bleeding) in future only the atypical closure of the duodenal stump according to the method of Nissen-Bsteh should be carried out. A bleeding ulcer should be operated within 48 hrs. If the bleeding needs more than 2500 ml blood substitute, this means a indication for a immediate operation.

Acute Disease↗