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Biomedical subjects

D Moussaoui

Publications and source records attributed to D Moussaoui.

At least 19 recordsLinked to original sources

Depression in mothers of burned children.

UNLABELLED: The treatment of burned children needs to address also their psychic state. Since the child's emotional state depends heavily on the emotional state of its parents, especially the mother's, interest should also be focused on diagnosing and treating secondary psychiatric disorders in mothers of burned children. The AIM of this work was to study the prevalence of depression in mothers of burned children and its predicting factors. METHODS: The enrolment of mothers of burned children was done in the Burns Department, Ibn Rushd University Hospital in Casablanca, Morocco. Twenty-eight mothers of seriously burned children agreed to participate in this study. A psychiatric interview was conducted after informed consent was obtained. The mothers completed a questionnaire; the diagnosis was made according to DSM IV criteria using the Mini International Neuro-psychiatric Interview (MINI). The Hamilton Depression Rating Scale and the Hamilton Anxiety Rating Scale were used to evaluate respectively the intensity of depression and the level of anxiety. Social functioning was assessed by the Global Assessment of Functioning scale (GAF). The minimum time interval between the child's being burned and the interview with the mother was one month. RESULTS: The prevalence of depression was 35.7%, which is much higher in the mothers of burned children as compared to the general population. Several risk factors were found such as: several burned children or burn of the only child, severity and complications of burn, and the socio-economic level. CONCLUSION: Depression is a common disorder in mothers of burned children. Thus early screening for depression in mothers and psychological and psychiatric support must be provided in conjunction with the treatment of the burned child.

Adolescent↗

Prevalence of postpartum depression in a Moroccan sample.

The aim of the present study was to determine the prevalence and factors associated with post-partum depression among Moroccan mothers. The authors interviewed 144 mothers at 2 and 6 weeks, and at 6 and 9 months after delivery. They used the Mini International Neuropsychiatric Interview (M.I.N.I.) and the Arabic version of Edinburgh Postnatal Depression Scale (EPDS). Using the M.I.N.I., 18.7% met DSM-IV criteria for depressive disorder in the second week after childbirth. Using a cut-off score of 12, the EPDS indicated a sensitivity and specificity of 92% and 96% respectively. Depressive disorder was significantly associated with pregnancy complications, stressful life events during pregnancy, baby's health problems, and poor marital relationship. The subsequent point prevalences were 6.9%, 11.8% and 5.6% respectively at 6 weeks, 6 and 9 months. Postnatal visits were effective in the identification of Moroccan depressed mothers.

Adult↗

Moroccan colloquial Arabic version of the Mini International Neuropsychiatric Interview (MINI): qualitative and quantitative validation.

The validation of mini international neuropsychiatric interview (MINI) into Moroccan Colloquial Arabic language demonstrated good psychometric properties. The concordance between translated MINI's and expert diagnoses was good with kappa values greater than 0.80. The reliability inter-rater and test-retest were excellent with kappa values above 0.80 and 0.90, respectively.

Arabs↗

Post-traumatic stress disorder in burned patients.

UNLABELLED: The essential feature of post-traumatic stress disorder is the development of characteristic symptoms following exposure to a traumatic stressor involving direct personal experience of an event that involves threat of death oactual r serious injury, or other threat to one's physical integrity; or witnessing an event that involves death, injury, or a threat to physical integrity of another person; or learning about unexpected or violent death, serious harm, or threat of death or injury experienced by a family member or other close associate (DSM IV). The aim of this work is to assess the prevalence of post-traumatic stress disorder (PTSD) among the burned victims and its predicting factors. METHODS: Patients were recruited at the Burns Department in the Ibn Rushd University Hospital during the period between 1 October 1998 and 1 October 1999. All patients were psychiatrically interviewed and answered a questionnaire. The diagnosis of PTSD was done according to DSM IV criteria. Results were analyzed on Epi info software. RESULTS: Sixty patients gave their consent to participate in this study. The 23.3% met criteria for PTSD and 55% for major depressive disorder. In short, PTSD was related to age, explosion of gas containers for cooking purposes, depression and low social functioning. Otherwise, no relationship was found between PTSD and gender, length of hospitalization or severity of burn. CONCLUSION: Post-traumatic stress disorder remains a poorly known entity by clinicians and under-diagnosed in burned patients. Considering the frequency of this pathology, an anti-depressant treatment and a psychotherapeutic relationship are necessary to improve the health and the quality of life of these patients.

Adolescent↗

Stability of exploratory eye movements as a marker of schizophrenia--a WHO multi-center study. World Health Organization.

The exploratory eye movements of patients with schizophrenia reportedly differ from those of patients without schizophrenia and healthy controls. In an attempt to determine whether exploratory eye movements provide valid markers for schizophrenia, the present collaborative study was conducted in six countries to analyze the stability of and variation in the following parameters of exploratory eye movements: the number of eye fixations (NEFs) and mean eye scanning length (MESL) in a retention task; the cognitive search score (CSS) that indicates how frequently the eye focused on each important area of a figure in order to recognize it in a comparison task; and the responsive search score (RSS), which reflects the frequency of eye fixations on each section of a figure in response to questioning in a comparison task. In addition, we investigated the validity of the currently employed discriminant function to extract a common feature of schizophrenia by applying it to the findings of the present study. The exploratory eye movements of 145 patients with schizophrenia, 116 depressed patients and 124 healthy controls at seven WHO collaborative centers in six countries were measured using eye mark recorders during viewing of stationary S-shaped figures in two sequential tasks. The RSSs of patients with schizophrenia were found to be significantly lower than those of depressed patients or healthy controls irrespective of geographical location, with no significant difference existing between the RSSs for depressed patients and those for healthy controls. By inserting the RSS and NEF data for each subject into the formula used to calculate discriminant function, patients with schizophrenia could be discriminated from depressed patients and healthy controls with a sensitivity of 89.0% and a specificity of 86.7%. The RSS is an exploratory eye movement parameter that detected schizophrenia irrespective of culture, race and various other subject variables. Furthermore, it is indicative of the stable, significant difference that exists between subjects with and without schizophrenia. The results of discriminant analysis confirm the previously reported validity of discriminant function.

Adult↗

Quality of life in treated and never-treated schizophrenic patients.

OBJECTIVE: To evaluate quality of life (QOL) among treated and never-treated schizophrenic patients. METHOD: QOL ratings were obtained for (a) 112 Moroccan participants with schizophrenia who had never received neuroleptic medications, (b) matched samples of chronically-medicated schizophrenic patients in Morocco and the United States and (c) matched community controls in both countries. RESULTS: QOL ratings were generally higher for US groups, although Moroccan controls obtained higher ratings than US controls for some domains. QOL ratings were higher for controls compared to patients within each country, although US patients' scores were similar to controls on some dimensions. We found no differences between treated and untreated Moroccan patients for any QOL domain, although relationships among predictors were different. CONCLUSION: Within the context of Moroccan culture, benefits of medications alone are not evident in QOL scores. QOL appears to be a complex construct influenced by different factors within each of the groups studied.

Adolescent↗

[Depression, suicidal ideation and schizophrenia].

UNLABELLED: The aim of this study was to find out the prevalence of depressive symptoms in patients with schizophrenia, with a special emphasis on suicidal thoughts and behaviors. 183 schizophrenic patients, according to ICD-10 criteria, were included. The interview was done by a psychiatrist using a questionnaire (socio-demographic data, premorbid functioning, schizophrenic and depressive antecedents and current depressive and suicidal thoughts and behaviors). The mean age was 34.3 +/- 8 years; 90% of the sample were males; 12.6% were married and 17% had children. RESULTS: The mean age at onset of the illness was 24 +/- 5.9 years and its mean duration was 4.8 +/- 1.3 years. The paranoid type was found in 78% of cases, and the schizo-affective one in 7.8%. During the assessment, 44.3% of the patients had depressive symptoms, 2.7% of them had suicidal ideas and 5% had a specific plan to implement them; 40% of the patients with suicidal ideas had a depression or had a painful consciousness of their illness. These results confirm the ones of other studies in the field: depression is frequent among patients with schizophrenia. An emphasis should be put on the necessity of treating both conditions when they co-exist in the same patient.

Adult↗

Movements in never-medicated schizophrenics: a preliminary study.

Descriptions of schizophrenia dating to the beginning of this century include mention of abnormal movements which are similar to tardive dyskinesia (TD), currently thought to be sequelae of neuroleptic medication. In order to examine the extent to which such movements might appear in the normal course of schizophrenia, we examined a sample of 22 never-medicated DSM-III-R schizophrenics who presented for treatment at a psychiatric center in Casablanca, Morocco. Duration of illness in this sample ranged from 1 to 10 years. Patients were assessed for choreoathetoid movements using the Abnormal Involuntary Movement Scale (AIMS). Videotaped and live examinations were rated by the investigators. Three patients (14%) met research diagnostic criteria for probable SD. Mild movements in one body part (AIMS = 2) were seen in an additional five (23%) patients. The movements were characteristic of TD, although their somatic distribution differed from previous studies. Total AIMS score increased with age and duration of illness (r = 0.64, P < 0.01). These findings suggest that choreoathetoid movements may appear spontaneously in patients with schizophrenia.

Adolescent↗

[The Sidi Frej maristan at Fez].

Sidi Frej's maristane or Fez maristane is Marocco's main and famous maristane. It is Mérinide dynasty's maristane; its rising, apogee and worse growing are close to the extent and further ruin of this dynasty. This maristane was built by Sultan Abou Youssouf Yacoub, about 1286, imitating a merinide's architectural design in shape of Spanish architecture. In another way, Sidi Frej's maristane was a pattern for many other maristanes in Marocco or in Spain. Since the XVe century, the Merinide Sultan Abou Said Othman II must sell every maristane's properties in order to fit out his troops. Then, the maristane became a mad-house. In 1943, maristane's building burnt. A Kissaria was built at the same place and patients were removed to another maristane named Sidi Frej's new maristane at Bab Khoukha.

History, Medieval↗

Biological study of alcohol dependence syndrome with reference to ethnic difference: report of a WHO Collaborative Study.

Inherited deficiency of acetaldehyde dehydrogenase type I (ALDH-I) was found in 43% (50/117) of normals, 33% (27/82) of schizophrenics, but only 4% (5/113) of alcoholics among Japanese. The ALDH-I deficiency was never found, however, in 146 mostly schizophrenic subjects from Europe (Basel, Moscow, Zagreb), Australia (Nedlands), India (Lucknow), Morocco (Casablanca) and Mexico (Mexico City). It was demonstrated that ALDH-I deficiency produces the flushing syndrome which inhibits the development of drinking habit and alcohol dependence syndrome.

Alcoholism↗

[Epidemiology of tardive dyskinesias in the Maghreb].

The most prescribed type of psychotropic medication in maghrebian psychiatry is neuroleptics. It is therefore legitimate to study the epidemiology of the most frequent side-effect of long-term treatment with neuroleptics: Tardive Dyskinesia (TD). At the moment, a collaborative study is under way on epidemiology of TD within the framework of the Maghrebian Association of Biological Psychiatry; several studies have also been conducted on this topic in the University Psychiatric Centre Ibn Rochd, Casablanca, Morocco in 1984, 1986 and 1987. For the maghrebian study, only preliminary results from Tunis will be presented. These studies have been interested in two epidemiological aspects: prevalence of TD in hospitalized and out-patients treated with neuroleptics; prevalence of TD-like movements among never treated schizophrenics. The assessment tool used for all the studies was the Abnormal Involuntary Movement Scale (AIMS). Main results of these studies are: 1) General prevalence of TD and risk factors in neuroleptized patients: In Tunis, Douki and Benamor in their on-going study, found a general prevalence of 20.50% (N = 200 in patients). A multi-factor analysis showed that risk factors are (in decreasing order): female gender, age above 60, associated depression, total duration of neuroleptic treatment above 20 years, a frequently discontinued treatment, shock therapies in antecedents or associated, a diagnosis of non schizophrenic psychosis, haloperidol intake below 25 mg and fluphenazine depot above 100 mg daily. In Casablanca, in 1984, Chorfi found a general prevalence of 10% (N = 50 out-patients). In 1986, Bentounsi found a 14.50% prevalence in Casablanca (N = 400 out-patients) and 63.97% in the oldest psychiatric hospital in Morocco in Berreshid (N = 605 in-patients).(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗