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Biomedical subjects

D N Gangwar

Publications and source records attributed to D N Gangwar.

At least 19 recordsLinked to original sources

Ocular manifestations of Wegener's granulomatosis in north India.

Evidence of ocular involvement was found in seven of eleven patients with histologically confirmed Wegener's granulomatosis. Pain (7/7), redness (6/7), scleritis (5/7), reduced visual acuity (5/7), episcleritis (5/7), uveitis (3/7), proptosis, sclerokeratitis and conjunctivitis (2/7) each were the major ophthalmological features. One patient each had bilateral corneoscleral ulcers, eyelid infiltration, scleromalacia perforans and epiphora. Corneal, scleral and uveal tract involvement was observed more frequently than has been described in the literature. These complications responded favourably to treatment with cyclophosphamide and corticosteroids. Treatment was delayed as most of these patients were diagnosed, initially, to be suffering from tuberculosis.

Adolescent↗

Enterovirus 70 acute hemorrhagic conjunctivitis--sporadic cases.

Acute hemorrhagic conjunctivitis (AHC) has been reported in epidemics. This is a report of 29 sporadic cases of AHC recorded over a period of two years after the 1981 epidemic in and around Chandigarh. A rapid and simple immunofluorescence test was developed and standardized in our Institute for the diagnosis of AHC. It was used for epidemiological monitoring of cases and to establish the diagnosis in suspected cases of AHC reporting after the epidemic. The clinical picture of epidemic and sporadic cases is compared.

Acute Disease↗

Cilioretinal artery occlusion: a case report.

A young man had an occlusion of the cilioretinal artery. Recirculation in the vessel was established within 48 hours. The retinal damage has been permanent with no improvement in visual acuity. Fluorescein angiography during the stages of occlusion and established recirculation have been described. Vascular spasm of a short posterior ciliary artery due to smoking is the likely causal factor. The site of obstruction and the hemodynamic factors have been discussed.

Adult↗

Immunofluorescence test for the epidemiological monitoring of acute haemorrhagic conjunctivitis cases.

An epidemic of acute haemorrhagic conjunctivitis (AHC) occurred in and around Chandigarh, north India, during June, July and August 1981. Considering the difficulty of virus isolation, the indirect immunofluorescence test was used for the demonstration of virus-specific antigen in the cytoplasm of exfoliated conjunctival cells, using reference antisera. The epidemic appeared to be primarily due to enterovirus type 70. The method was found suitable for the rapid diagnosis of AHC cases and for detecting subclinical infection among healthy subjects and convalescent carriers. During follow-up, it was observed that some of the AHC cases were shedding virus-infected conjunctival cells for a prolonged period, even after clinical recovery and during convalescence, before they became free from virus. In the absence of virus isolation, this method can be considered as suitable for the epidemiological monitoring of AHC.

Acute Disease↗

Fuchs' heterochromic cyclitis: some observations on clinical picture and on cataract surgery.

In a study of 33 patients of heterochromic cyclitis, some unusual clinical features were observed. In many cases the iris was feltlike, month eaten, and associated with gelatinous nodules at the pupillary border or over the surface of iris stroma. An association of pseudoexfoliation of the lens capsule with bilateral heterochromic cyclitis was noted. Twenty-one eyes were subjected to cataract surgery. Hyphema (23.6%) and phacoanaphylactic uveitis (9.5%) were the main postoperative complications.

Adolescent↗