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Biomedical subjects

D N Mendhekar

Publications and source records attributed to D N Mendhekar.

31 records · Page 2Linked to original sources
PubMed2004

Bulimia nervosa.

Although there is a lot of information coming up to explain the pathogenesis of anorexia nervosa, yet little is know about bulimia nervosa in Indian literature. This case report highlights the typical presentation of a case of bulimia nervosa in an adolescent girl, where bulimia symptoms were preceded by anorexic behavior. Our case showed clinical similarity with the diagnostic criteria of the available classification system. The absence of self-evaluation for body weight and shape in this case be explained on the basis of cultural factors. To some extent, initial anorexic behavior could have played a role in etiopathogenesis of bulimia nervosa.

Adolescent↗
PubMed2004

Effect of risperidone on prolactinoma--a case report.

Risperidone induced galactorrhea and hyperprolactinemia have been reported but its role in the growth of prolactinoma is not yet conclusive, due to extreme rarity of such cases. We describe a woman, suffering from Bipolar Disorder-manic episode, who exhibited prolactinoma while on risperidone therapy. The withdrawal of risperidone resulted in disappearance of prolactinoma though her prolactin level remained elevated along with persistent galactorrhea. The change to olanzapine therapy did not show much change in serum prolactin level and galactorrhea. Ultimately, only adding of bromocriptine resulted in disappearance of symptoms of prolactinemia and normal serum prolactin level was achieved and galactorrhea stopped. Further study is recommended to find out relationship between the growth of prolactinoma and risperidone.

Adult↗
PubMed2004

Chronic but not resistant mania: a case report.

OBJECTIVE: There are many nuances of elevated mood states. At times, it becomes very difficult to diagnose a case of mania because of personality style of the patient superimposed on a cyclothymic or hyperthymic temperament. Such cases may become chronic if timely intervention is not received. We describe a case of chronic mania of 48 years of duration. METHOD: A case report. RESULTS: A 65-year-old male was admitted with history of mania for around five decades. The illness commenced at prepubertal age and was continuous without any residual symptoms of note. During the course of illness, he got involved in many devastating socio-politico-legal complications. He showed good response to treatment and is currently maintained well without medication. In this case we also described some psychosocial features that may have been responsible for the chronicity of the illness. CONCLUSION: We highlighted the need for correctly identifying chronic mania, early intervention and increasing treatment awareness. This case was not treatment resistant, suggesting that chronicity per se should not denote poor outcome.

Age of Onset↗
PubMed2003

Sertraline-induced hypomania: a genuine side-effect.

OBJECTIVE: Antidepressants including selective serotonin reuptake inhibitor (SSRI)-associated mania or hypomania has been well documented in the literature but these patients with switch have either mood disorders or various risk factors for bipolar disorder. This case report examines SSRI-induced hypomania in a patient with dissociative disorder and highlights hypomania as a genuine side-effect of sertraline rather than a switch. METHOD: A 23-year-old female patient with dissociative disorder has been described. RESULTS: Hypomanic symptoms emerged during treatment with sertraline at the dose of 50 mg/day after 3-4 days of initiation of therapy and had complete recovery within 7 days after stopping sertraline. CONCLUSION: In the absence of risk factors for manic switch, sertraline-induced hypomania may be a true side-effect of drug.

Adult↗
PubMed2002

Olanzapine and pregnancy.

This report focuses on the case of a pregnant woman with a bad obstetric history who developed psychosis at the 23 rd week of gestation. She was treated with olanzapine from the 24th week until 10 days prior to delivery. No adverse events occurred during pregnancy or delivery. The Apgar score was 8/10 at one minute and 9/10 at 5 minutes.

Adult↗