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Biomedical subjects

D Novak

Publications and source records attributed to D Novak.

At least 55 records · Page 3Linked to original sources
PubMed1976

[Radiological aspects of the basal cell naevus syndrome (Gorlin-Goltz syndrome) (author's transl)].

The radiological features of the basal cell naevus syndrome (Gorling-Goltz syndrome) are described, based on four of our own cases and 105 collected from the literature. Multiple cysts in the lower or upper jaw are found in 92% and 35% respectively. Anomalies of ribs are present in 45%, calcification of the falx in 49% and a scoliosis of the spine in 32% of cases. In our four patients, multiple small cysts were found in the bones of the hands and of the arms. These changes have not been previously described.

Abnormalities, Multiple↗
PubMed1976

[Pharmaco-angiography with angiotensin (author's transl)].

The results of pharmacoangiography using angiotensin were compared with the findings in 101 patients during selective angiography of the kidneys (48 cases), the pancreas and liver (46 cases) and of peripheral soft tissue lesions (7 cases). Angiotensin in a dose of 0.5--l mug (renal artery), 1--5 mug (coeliac artery) and 5--10 mug (peripheral vessels) was found to be a constant and potent vaso-constrictor in 99% of cases. Intraarterial injection of angiotensin improved evaluation in 18 out of 27 cases (66%) with a final diagnosis of a tumor, in 18 out of 22 patients (77%) with cysts and in 16 out of 24 (66%) with an inflammatory process. In three out of 27 cases (11%) an angiographic diagnosis was possible only after using pharmacoangiography. The use of angiotensin represents a valuable possibility of clarifying otherwise uncertain angiographic diagnoses. This is particularly the case where superselective catheterisation is impossible.

Adenocarcinoma↗
PubMed1976

Selective renal occlusion phlebography with a balloon catheter.

Technique of selective renal occlusion phlebography is described. For the temporary occlusion of the renal vein a Swan-Ganz or Dotter-Lucas balloon catheter are used. The balloon catheter is directed into the renal vein using a Desilets-Hoffmann or EDSLAB introducer. Occlusion of the renal vein is achieved by insufflation of 2-3 ml. air into the balloon of the catheter. Selective renal occlusion phlebography leads to optimal retrograde opacification of the renal venous system.

Catheterization↗
PubMed1976

Hepatic occlusion venography with a balloon catheter in patients with end-to side portacaval shunts.

Hepatic occlusion venography with the aid of a Swan-Ganz balloon catheter represents a significant improvement in the radiographic demonstration of hepatic veins and their alteration in liver disease. It is simple to perform and can be combined with other hemodynamic examinations (e.g., hepatic vein pressure measurements). In this way the morphologic and hemodynamic changes in the pre- and postoperative evaluation of patients with portal hypertension can be investigated simultaneously. The method allows optimal demonstration of large branches of hepatic veins. Overloading of small areas of liver parenchyma with concentrated contrast medium, as in wedged hepatic venography, is avoided. Previously unknown portosplanchnic anastomoses developing after end-to-side portacaval shunt were demonstrated in seven of eight patients using this method. The frequency and size of these collaterals suggest possible hemodynamic and clinical significance.

Adult↗
PubMed1976

[Present status of pharmacoradiology of the gastrointestinal tract (author's transl)].

Based upon the findings in over 1200 patients, technique, indication and validity of pharmacoradiology in examinations of esophagus, stomach, duodenum, small and large intestine are critically evaluated and summarized. Dosis, effects, side effects and contraindications of the mostly applied pharmaca (Buscopan, Pro-Banthine, Paspertin, Glucagon, Cholecystokinin and Caerulein) are listed. The value of pharmacoradiology of the gastrointestinal tract for clinical roentgenology is stressed.

Butylscopolammonium Bromide↗
PubMed1976

[Visceral and peripheral pharmacoangiography with angiotensin and bradykinin (author's transl)].

In a prospective study of 156 patients a total of 110 pharmacoangiographic examinations using Angiotensin and 46 investigations with Bradykinin were performed. In 21 cases both pharmaca were applied. In 111 patients with pathologic findings (tumors, cysts and inflammatory lesions) diagnostic information compared with conventional angiography, was improved in 80, equal in 26 and reduced in 5 cases. In 21 studied patients using Angiotensin and Bradykinin, the overall diagnostic information was improved. Angiotensin is a suitable pharmacon in demonstration of malignant lesions. Bradykinin improves the demonstration of vessels affected by local inflammation and allows better visualization of the veins. The application of both pharmaca may help in certain cases to differentiate between inflammatory and malignant lesions.

Abscess↗
PubMed1975

[Acceleration of passage through the small intestine by caerulein (author's transl)].

Passage through the small intestine was significantly accelerated after intramuscular injection of ceruletide (synthetic caerulein, F.I. 6934), 0.50 to 0.75 mug/kg body-weight. Average passage took 62 +/- 41 min (106 patients, with various suspected or demonstrated small-intestinal involvement, excluding malabsorption syndrome, sprue or collagen diseases) after caerulein, while in a control group of 83 patients with radiologically normal small intestine it was 126 +/- 62 min (P less than 0.001). In 75% of patients there was no evidence of induced change in radiological pattern of the small intestine. Increased local contractions were observed in a quarter of patients, but did not impair the diagnostic interpretation.

Adolescent↗
PubMed1975

[Hypotonic oesophagography using propanthelin bromide (Pro-Banthine) (author's transl)].

Hypotonic oesophagography was performed in 149 patients after the intravenous injection of propanthelin bromide (Pro-Banthine). An injection of 0.25-0.50 mug/kg body weight led to hypotonia of the oesophagus in 96% of cases. During hypotonia, it was possible to demonstrate oesophageal varices in 24 out of 27 patients, and small hiatus hernias in 10 out of 23 patients. Conventional examination demonstrated oesophageal varices in only 13 of the 27 cases and hiatus hernias in four out of the 23 cases. Hypotonic oesophagography thus leads to an improvement in the accuracy in the diagnosis of oesophageal varices and small hiatus hernias. Following injections of Pro-Banthine, transient side effects were observed consisting of tachycardia, difficulties in accomodation, reduction in salivary excretion and difficulties in micturition. Pro-Banthine is contra-indicated in the presence of glaucoma, severe cardiac and circulatory diseases and urinary obstruction.

Adult↗