PubMed Health⌕ Search

Biomedical subjects

D O Mazur

Publications and source records attributed to D O Mazur.

8 recordsLinked to original sources

Photic maculopathy after extracapsular cataract surgery. A prospective study.

Photic retinal injuries have been described after surgical exposure to the intense illumination systems of operating microscopes. The overall incidence of such injuries has been postulated at less than 10%. The authors prospectively studied 43 consecutive patients to determine the incidence of photic macular injuries during cataract surgery. Patients underwent complete ophthalmic examinations, fundus photography, and oral fluorography before and after surgery. Photic macular injuries developed in 12 of 43 eyes (28%) as a result of intraocular surgery. This incidence is much higher than previous estimates. The association with possible risk factors, cystoid macular edema, and the effect of these injuries on final visual acuity are discussed.

Cataract Extraction↗

Clinical and immunopathological studies of pars planitis in a family.

We examined a family in which two brothers with identical HLA typing have pars planitis with snowbanking. Immunopathological studies of one of their eyes showed that in the area of snowbanking over the pars plana there was mild to moderate inflammatory cell infiltration, consisting of mostly Pan T (Leu 4+) lymphocytes. The ratio of T helper/inducer to T suppressor/cytotoxic cells was approximately 10:1. Few macrophages (OKM1+) were identified. Very few B cells and no NK cells were observed. Some retinal vessels had a perivascular infiltration consisting of mostly T lymphocytes. Most of the inflammatory cells bore class II antigens (HLA-DR+), while T cells bore few IL-2 receptors (anti-TAC+). The snowbank consisted mainly of glial elements (GFAP+) and basement membrane components (type IV collagen and laminin) with the predominant cell the Müller cell (Mü+). A site of inflammation at the iris-ciliary body junction also stained for B cells (Leu 14+). These findings suggest that the snowbank could be formed by the glial elements of the peripheral retina. The chronic inflammation in pars planitis appears to consist of helper T cells, both in the pars plana, and the retinal vasculature.

Adolescent↗

Ocular trauma treated by vitreous surgery.

One hundred three consecutive patients with ocular trauma who were not candidates for conventional ocular surgical treatment were treated with vitreous surgical techniques. Follow-up of the patients from 12 to 60 months following vitreous surgery, with an average follow-up of 22 months. Data concerning the timing of vitreous surgery following injury, the location and severity of the injury, and other complicating factors that have an effect on eventual results are presented.

Adolescent↗

Choroidal neovascularization in children: report of five cases and literature review.

Choroidal neovascularization is rare in the pediatric population. It has been associated in this age group with a variety of conditions. Increasing ability to treat these neovascular lesions with laser photocoagulation makes early recognition very important for visual preservation. An overview is presented, including an updated list of conditions associated with choroidal neovascularization in children and adolescents. Guidelines to recognition, parent and patient instructions, and the selective use of fluorescein angiography are emphasized. Five illustrative cases are highlighted, including a 10-year-old boy successfully treated with krypton laser photocoagulation near the fovea.

Adolescent↗