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Biomedical subjects

D Obel

Publications and source records attributed to D Obel.

6 recordsLinked to original sources
PubMed1991

Protein kinase C subtypes in human neutrophils.

Protein kinase C from rat brain and human neutrophils was chromatographically separated on a hydroxylapatite column connected to a high-performance liquid chromatography (HPLC) system. Protein kinase C from rat brain was separated into three peaks (types I, II, and III). In contrast, only two types were obtained from human neutrophils matching type II and type III in brain. In cell membranes from unstimulated human neutrophils type III was predominant, but mainly type II was translocated to the membranes upon stimulation with phorbolmyristatacetate (PMA). Both types were equivalently activated by phosphatidylserine, diolein, and magnium and presented identical Km for ATP.

Animals↗
PubMed1985

Buprenorphine-supplemented anaesthesia. Influence of dose on duration of analgesia after cholecystectomy.

Fifty-one patients undergoing cholecystectomy received a single dose of buprenorphine 4.5-12 micrograms kg-1 at induction. Median duration of analgesia after surgery was 6 h. Multiple regression analysis showed the duration of analgesia to be slightly dependent on the age of the patient. No relationship was found between the duration of analgesia and the weight-related dose of buprenorphine, the age, sex or body weight of the patient, the duration of anaesthesia, or the dose of droperidol or thiopentone administered.

Adjuvants, Anesthesia↗
PubMed1985

Efficacy of the ejector flow-meter. A scavenging device for anaesthetic gases.

Measurements of air concentrations of nitrous oxide and halothane in the breathing zone of the anaesthetist and the operating-room nurse were carried out during inhalation anaesthesia with a Mapleson D system. Gas removal was performed from inside the breathing system at the same rate as that of the fresh gas inflow by means of an ejector flow-meter. The concentrations of nitrous oxide and halothane were maintained below the Danish Threshold Limit Values of 100 and 5 parts per million, respectively, by using this type of scavenging. When these anaesthetics were used simultaneously, the reduced Threshold Limit Values were not exceeded during endotracheal anaesthesia.

Air Pollutants, Occupational↗