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Biomedical subjects

D P Babbitt

Publications and source records attributed to D P Babbitt.

At least 19 recordsLinked to original sources

Five stages of joint disintegration compared with range of motion in hemophilia.

The Arnold-Hilgartner roentgenographic method, categorizing hemophilic arthropathy into five stages, was evaluated in 270 hemophilic joints in terms of range of motion. The early stages, 0 or normal, Stage 1, and Stage 2, were associated with a 90% of normal or greater range of motion in the elbow, knee, and ankle, the three joints most commonly affected and studied here. These stages also showed the greatest variation between double-blind staging. The elbow showed the greatest degree of degeneration with the least loss of range of motion, whereas just the opposite was true for the ankle with the knee intermediate. With advanced arthropathy the mean arc for the elbow at Stage 3 was 127 degrees, Stage 4 was 100 degrees, and Stage 5 was 78 degrees. For the knee, Stage 3 was 121 degrees, Stage 4 was 95 degrees and Stage 5 was 47 degrees. For the ankle Stage 3 was 55 degrees, Stage 4 was 44 degrees, and Stage 5 was 22 degrees. The early loss with no exceptions was extension of the elbow, flexion of the knee, and dorsiflexion of the ankle. Loss of cartilage joint space was the most important roentgenographic finding related to range of motion.

Adolescent↗

A precise technique to localize pulmonary-pleural air leaks.

A bubblegram technique is described for identification of air leaks in persistent pneumothorax by introducing water-soluble contrast medium into the pleural space. The technique proved useful in eight children examined for persistent air leaks.

Air↗

Technetium-99m biliary imaging in pediatric surgical problems.

The results of scintigraphic imaging of the hepatobiliary system with 99mTc-PIPIDA (IDA derivative p-isopropylacetanilidoiminodiacetic acid) in forty children are reported. 99mTc-PIPIDA imaging is a noninvasive, rapid, safe examination that provides both functional and anatomical information about the hepatobiliary system. Although interpretation is limited by elevated direct serum bilirubin, this agent allows diagnostic information to be obtained with direct serum bilirubin levels up to 8 mg/dl.

Adolescent↗

Extraosseous uptake of 99mtechnetium methylene diphosphonate: neuroblastoma or radiation therapy.

A child with a ganglioneuroblastoma and tumor uptake of 99mtechnetium methylene diphosphonate (99mTc-MDP) is presented. After surgical removal of an encapsulated tumor and radiation therapy, an interval bone scan demonstrated the same presurgical abnormality. Awareness of abnormal uptake of 99mTc-MDP in irradiated renal tissue prevents interpreting radiation nephritis as recurrent tumor.

Bone Neoplasms↗

Evaluating the multicystic kidney.

The multicystic kidney is the most common renal mass in the newborn child. The entity represents 50-65% of all abdominal masses presenting during infancy. The use of Tc-99m-glucoheptonate renal imaging and ultrasonography has improved the diagnostic accuracy in this condition. Four patients with unilateral multicystic kidneys are discussed. The diagnostic and pathologic characteristics of the multicystic kidney are described.

Humans↗

Radionuclide "Dance Sign.".

The authors describe the radionuclide characteristics of the "Dance Sign." The "Dance Sign" is an uncommon but reliable observation found on physical examination in patients with intussusception.

Adolescent↗

Multiple bladder diverticula in Williams "Elfin-Facies" syndrome.

Twenty-three children with Williams "elfin-facies" syndrome were reviewed. A striking incidence of multiple bladder diverticula was found (8 children of 14 who had voiding cystourethrograms). The diverticula were usually not identifiable on excretory urography. Children generally have a low incidence of bladder diverticula (excluding "Hutch" diverticula), especially multiple diverticula; thus one should strongly consider the diagnosis of Williams syndrome and other connective tissue diseases when multiple bladder diverticula are identified.

Abnormalities, Multiple↗

Anatomic observations and etiologic and surgical considerations in choledochal cyst.

Twenty-five operative and postoperative cholangiograms in children with choledochal cysts indicated an intimate relationship between these cysts and anomalous pancreatico-biliary ductal junction. In all of these patients the distal main pancreatic duct (MPD) is excluded from the sphinctor of Oddi mechanism and free reflux of pancreatic juice up the biliary tree occurs. This leads to chronic cholangitis, which is presumed to be responsible for the formation of the choledochal cysts. Abrupt and intense exposure of the common bile duct (CBD) to pancreatic reflux may cause perforation and bile peritonitis. Long-standing exposure may induce malignant transformation in the choledochal cyst. Total cyst excision and separation of the biliary system from exposure to pancreatic reflux is suggested as the procedure of choice. Long-term results and metabolic and digestive consequences of this operation are yet to be determined.

Cholangiography↗