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Biomedical subjects

D P Finnerty

Publications and source records attributed to D P Finnerty.

9 recordsLinked to original sources

Treatment of persistent penile erection and priapism using terbutaline.

The recent finding of terbutaline as the treatment of choice to manage intraoperative penile tumescence with the patient under anesthesia (general and regional) has prompted us to use this beta-2 agonist (5 mg. orally) for persistent penile erection and priapism resulting from injection of pharmacological agents, such as phentolamine, phenoxybenzamine and papavarine, into the penis for erectile impotence. The drug also has been used successfully (0.25 to 0.5 mg. intravenously or subcutaneously) to treat priapism developing despite a cavernosum-spongiosum shunt procedure. This and other pure beta 2 agonists will have an important role in the treatment of undesirable and painful penile erection, alone or in association with other invasive and noninvasive intervention.

Adult

Splenic gonadal fusion.

Splenogonadal fusion is a rare anomaly to be included in the differential diagnosis of testicular masses. It is often associated with congenital defects, including peromelia and micrognathia. A case is presented and the literature reviewed.

Gonadal Dysgenesis

Periurethral abscess.

From 1963 to 1985, 63 periurethral abscesses were treated in 47 men. The records were reviewed to characterize the natural course of the disease. The most common predisposing factors were a history of gonorrhea, previous periurethral abscess and urethral stricture disease. Treatment consisted of abscess drainage, suprapubic urinary diversion and intravenous antibiotic therapy, consisting of an aminoglycoside and a cephalosporin. Mortality was 1 of 63 patient hospitalizations (1.6 per cent). Improved survival over historical cohorts is attributed to the availability of better antibiotics and medical support.

Abscess

Transluminal balloon dilation of ureteral strictures.

Ureteral strictures are uncommon problems in urological practice. The nonvascular application of the Grüntzig balloon catheter is proposed as an alternative to surgery in some of these patients. We treated 6 ureteral strictures in 5 patients by balloon dilation with an 83 per cent success rate.

Adult

Prostatic melanosis with involvement of benign and malignant epithelium.

We report an unusual case of prostatic melanosis. Grossly, the majority of prostatic chips contained areas of black discoloration. Microscopically, pigment was identified within the prostatic stroma, in benign prostatic ducts and within the cells of a well differentiated prostatic adenocarcinoma. The pigment was identified as melanin by histochemical methods and electron microscopy. The histogenesis of prostatic melanosis is discussed and it is proposed that the melanin pigment is derived from (aberrant) stromal melanocytes.

Adenocarcinoma