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Biomedical subjects

D P Popa

Publications and source records attributed to D P Popa.

At least 91 records · Page 5Linked to original sources

Results of an etiological therapy applied to patients with different localizations of herpes infection detected by immunofluorescence reaction.

An indirect immunofluorescence reaction was used for cytovirological diagnosis in 110 patients with different herpes-like clinical manifestations. The presence of herpes antigens type 1 and 2 was made evident in the exfoliated cells from 77% of the cases with recurrent herpes, in 68% of those with cutaneous and/or oral herpes, in 64% of the cases with keratoconjunctivitis and in 37.5% of the women with different genital diseases. Administration of specific antiherpes immunoglobulins and of the chemotherapeutic drug Flumidin to cases with positive immunofluorescence reactions led to improvement of the symptoms and even to clinical recovery.

Amidines↗

Rapid detection by immunofluorescence of multiple viral infections in patients with keratitis.

The presence of 12 viral (herpes 1 and 2, influenza A(H1N1), A(H3N2) and B, parainfluenza 1, 2, 3, adenovirus 5) and inframicrobial (Chlamydia, mycoplasma, Rickettsia burneti) antigens was investigated by direct or indirect immunofluorescence (IF) reactions in exfoliated conjunctival cells from 110 patients with nonbacterial keratitis and keratoconjunctivitis. A rapid etiological diagnosis could be obtained in 101 (92%) of the cases, parainfluenza and herpes antigens being the most frequently detected. In most of the cases the simultaneous presence of several antigens was made evident. Encouraging results were obtained by the application of a specific treatment based on the diagnosis provided by the IF reaction.

Antigens, Viral↗