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Biomedical subjects

D P Romeo

Publications and source records attributed to D P Romeo.

6 recordsLinked to original sources
PubMed1990

Misdiagnosis of the Zollinger-Ellison syndrome due to hyperlipidemia.

Most authorities feel that diagnosis of the Zollinger-Ellison syndrome is established when the serum gastrin level is greater than 1000 pg/mL (1000 ng/L) in a patient with gastric acid hypersecretion and clinical manifestations consistent with the diagnosis. A patient with recurrent peptic ulcer disease is reported who was thought to have had the Zollinger-Ellison syndrome based on two serum gastrin level measurements greater than 1000 pg/mL (1000 ng/L). Subsequent evaluation revealed the gastrin elevation to be spurious because the sample was hyperlipidemic. Lipemic serum samples may yield falsely elevated serum gastrin determinations as determined by radioimmunoassay.

Diagnostic Errors↗
PubMed1986

Pulmonary paragonimiasis: diagnostic value of pleural fluid analysis.

Pleural fluid studies showing a glucose value of less than 10 mg/dl, an LDH level greater than 1,000 IU/L, eosinophilia, a high protein value, and low pH are characteristic of paragonimiasis. In a patient with a pleural effusion and compatible clinical, radiologic, and serologic findings, pleural fluid analysis will allow diagnosis with reasonable certainty even in the absence of positive ova studies, and is useful in distinguishing paragonimiasis from tuberculosis.

Adult↗
PubMed1985

Acute colonic pseudo-obstruction: a possible role for the colocolonic reflex.

In diverse clinical settings, injury or impairment of the peripheral autonomic nervous system may cause acute colonic pseudo-obstruction. The mechanism has remained elusive since Ogilvie's original description. In classic Ogilvie's syndrome, colonic pseudo-obstruction is associated with malignant invasion of the prevertebral ganglia, and may be mediated through the colocolonic reflex, described in a guinea pig model. We have treated three patients with acute colonic pseudo-obstruction due to: 1) malignant invasion of the prevertebral plexus (classic or true Ogilvie's syndrome), 2) clonidine, and 3) herniorrhaphy under epidural anesthesia. In this paper, we discuss the possible role of the colocolonic reflex in the pathophysiology of acute colonic pseudo-obstruction, and the delineation of true Ogilvie's syndrome from the other many causes of acute colonic pseudo-obstruction.

Acute Disease↗