Leiomyosarcoma of the spermatic cord.
A case of leiomyosarcoma of the spermatic cord occurring in a 62-year-old man is reported. The English literature on the topic is briefly reviewed.
Biomedical subjects
Publications and source records attributed to D P Sarma.
A case of leiomyosarcoma of the spermatic cord occurring in a 62-year-old man is reported. The English literature on the topic is briefly reviewed.
A primary squamous cell carcinoma occurring in the prostate of a sixty-nine-year-old man is described. A radical excision that included cystoprostatectomy, total penectomy, scrotectomy, pubic symphysiectomy, and abdominoperineal resection of rectum was done. The patient died of systemic metastases six months after diagnosis. Review of the literature suggests that such a cancer of the prostate is rare, highly aggressive, and responds poorly to any mode of therapy. Histogenesis of this tumor remains controversial; however, it probably does not originate from the prostatic acinar cells.
A 56-year-old man had a deeply invasive leiomyosarcoma of the right buttock. Leiomyosarcomas of the skin and subcutaneous tissues are rare, and most occur on the extremities. Wide local excision is the therapy of choice.
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We report a case of human penile ossification with roentgenologic and histologic confirmation. The English literature is reviewed, and the pathogenesis of such a rare lesion is presented. Penile ossification appears to be an acquired metaplastic process occurring in an area of fibrosis.
Two cases of small cell carcinoma of the larynx are presented. The English literature is reviewed to update the various aspects of this rare tumor.
Radiologic evaluation disclosed a renal tumor and a calcified mass in the right kidney of a 45-year-old man. The resected kidney revealed that a renal cell carcinoma had invaded the renal pelvis and the polypoid intrapelvic portion had undergone calcification resulting in a pseudocalculus.
A rare case of synovial chondromatosis of the knee occurring in a 65-year-old man is reported. Electron microscopy of the lesion suggests that the cartilaginous nodules develop through a process of metaplasia from the stromal fibroblasts.
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Small-cell carcinoma of the prostate is rare, but lethal. We report on 2 cases and review another 6 cases reported in the English literature. Microscopically the tumor may be pure small-cell carcinoma like that seen in the lung or may have a mixed pattern of adenocarcinoma with small-cell carcinoma. This tumor most probably arises from the basal or reserve cells of the prostatic acini. The totipotential basal cells have dual capacity for differentiation into adenocarcinoma and small-cell carcinoma.
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Papillary carcinoma of the thyroid usually spreads to the lymph nodes. Vascular metastatic spread is unusual. We report a case of papillary carcinoma of the thyroid with extensive vascular dissemination and remarkable intraglomerular metastases to both kidneys.
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Sixty-seven cases of lung cancer occurring in men aged 75 or older were examined at autopsy. There is a similar incidence of epidermoid and small cell carcinoma, but a lower incidence of adenocarcinoma and a slightly higher incidence of large cell carcinoma in this elderly group of patients compared to the incidence of various histologic types occurring in patients of all ages. The various organs involved by metastatic tumor are similar to those seen in lung cancer in general; the overall metastatic disease is less widespread in the older group.
A 67-year-old man presented with signs and symptoms of obstructive jaundice. At autopsy, a hepatocellular carcinoma was noted to have obstructed both hepatic ducts and the common hepatic duct. Literature is reviewed to elaborate on this unusual manifestation of hepatocellular carcinoma.
Three patients with carcinoma of the first and the third part of the duodenum are reported. A review of the literature shows the diagnosis of this rare lesion of the duodenum is usually late. In order for surgical resection to be successful, suspicion of such a lesion and an aggressive workup is needed.
Autopsy records of ten patients aged 40 or younger with colorectal carcinoma were reviewed. The local and metastatic spread of the cancer was similar to that seen in colorectal cancers occurring in older people. Colorectal cancer in young people is biologically not more aggressive or virulent than that in older patients.