Evaluation of an innovative self-instructional program in the surgical subspecialties.
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Biomedical subjects
Publications and source records attributed to D P Yens.
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The undergraduate grade-point average, scores on the Medical College Admission Tests and Parts I and II of the examinations of the National Board of Medical Examiners, medical school grades, and membership in Alpha Omega Alpha, the medical honor society, were compared for four categories of undergraduate majors to determine whether nonscience preparation was a handicap for medical training. Data for nine complete classes at one medical school were used. The results indicated that nonscience students performed as well as or better than traditional science trained students on almost all performance measures. Implications for medical school admissions policies are discussed.
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BACKGROUND: We undertook a study to determine the incidence of hepatitis C in patients with persistent elevations of aminotransferases, either alanine aminotransferase (ALT) or aspartate aminotransferase (AST). METHODS: We conducted a retrospective review of medical records at the Family Practice Center from 1992 to 1993. Patients in whom aminotransferase levels were elevated 1.5 times normal for at least 6 months were eligible for the study. Sixty patients met our eligibility criteria. Patients were tested for hepatitis B and C and other possible causes of elevated aminotransferase levels. RESULTS: Of these 60 patients, 35 (58 percent) tested positive for hepatitis C virus by first-generation enzyme-linked immunosorbent assay (ELISA-I); 30 had positive results confirmed by second-generation recombinant immunoblot assay (RIBA-II). The other 5 patients were lost to follow-up, and their status was not confirmed. Of the 30 patients with a positive RIBA-II, 14 had liver biopsies showing chronic persistent hepatitis or chronic active hepatitis, both consistent with hepatitis C infection. Of the 60 patients, 2 (3 percent) had hepatitis B. None had active hepatitis B coexisting with hepatitis C. CONCLUSIONS: Our data show a much greater incidence of hepatitis C (50 percent) in our patients with chronic elevations of aminotransferase levels compared with data reported from previous studies.