Biomedical subjects

D Păduraru

Publications and source records attributed to D Păduraru.

13 recordsLinked to original sources

PubMedDate not supplied

[Intermesenteric anastomoses].

This work is based on dissection and the analysis of the arteriographies of two mesenteric arteries and it analyses the type of intermesenteric anastomoses and their importance in surgical practice. The morphological varieties of Riolan's arcade depends on its pillars, as well as on the eventual presence, especially in the middle part of the transversal mesocolon, of the secondary arcades; it seems that the colic wall necrosis depends less upon the location of the lesion or the level of the suture of the arcade, but more so on the stretch of the destruction of the mesocolon. The intermesenteric trunk, a second way of intermesenteric anastomoses is a embryological remaining, non-functional in normal conditions, but capable to partially or completely replace the Riolan's arcade when the later is sutured or interrupted.

Angiography↗

PubMedDate not supplied

[Hepatic artery variants originating from the superior mesenteric artery--the surgical implications].

The hepatic accessory (or aberrant) arteries appear as a consequence of modifications during the embryological development of the splanchnic arterial system. These arteries emerge from the first segment of the superior mesenteric artery and have a variable trajectory, of importance being the relations with the head of the pancreas and with the extra-hepatic biliary ducts. Taking into account the appreciable frequency of these arteries (19.5%), the relations and the surgical implications, I consider that the presence of these arteries should be determined mandatory by means of selective pre-surgical arteriography; when this procedure is not available the presence of extra-arteries emerging from the superior mesenteric artery (S.M.A.) can be speculated when pulsations in the free border of the lesser omentum are detected.

Angiography↗

PubMedDate not supplied

[The luteolytic action of prostaglandin F2-alpha analogues in guinea pig's ovary].

The role of prostaglandin at the level of the female genital system is multiple; they are involved in ovulation, luteolysis, contractility of the tube muscles, contraction of the gravid uterus, dilatation of the cervix. The synthetic analogous of the prostaglandin F2 alpha are utilized in a large area of treatments, for multiple purposes. The study was made on 2 lots with 10 non pregnant female guinea pig: the first lot was the witness lot and didn't receive any substance. The second lot received 100 micrograms/kg/day Isopropyl ester PGF2 alpha. The prostaglandin analogous produces vasodilating effects on the ovary blood vessels and luteolytic effects with the destruction of the ovarian follicles.

Animals↗

PubMedDate not supplied

[White-Bland -Garland syndrome: the maximum natural development of the coronary anastomosis ].

The anormalous origin of the left coronary artery from pulmonary artery (White-Bland Garland syndrome) is a very rare coronary malformation, having despite the great mortality in the early childhood, an adult form, characterized by minor symptoms and long course. This paradoxical situation is totally dependant to the complete development of the coronary anastomosis, allowing the right coronary flow to perfuse the left myocardium. The theory of the "terminal arterial perfusion" of the heart, still persistent in some monographs is meeting in this natural situation its strongest opponent argumentation. The coronary anastomosis, clearly visible by coronarography are large enough (in late stages) to inverse the flow in left coronary artery, filling the pulmonary artery. Is the coronary-pulmonary shunt, responsible for the majority of symptoms, in the 5th or 6th decade. The adult form of the White-Bland Garland syndrome is indicative for the maximum result we may hope to reach using the new revascularisation method for ischemic heart disease: new vessels formation and enhancing the coronary anastomosis by growth factors administration therapy.

Adult↗

PubMedDate not supplied

[Antenatal corticosteroid therapy and the effects on complications of prematurity].

UNLABELLED: The respiratory distress syndrome (RDS) in the preterm neonates is the most frequent cause of morbidity and mortality in neonatal units. Corticosteroids were shown to have multiple beneficial effects in maturing fetal surfactant and in decreasing the incidence and severity of RDS, intraventricular hemorrhage and necrotizing enterocolitis. MATERIAL AND METHODS: The authors studied 65 premies treated antenatally with corticosteroids versus 68 preterm neonates that didn't benefit from this therapy. All cases presented life threatening distress by various causes. There were evaluated the incidence of hyaline membrane disease, incidence related with gender, gestational age, the severity of respiratory distress (Silverman score), influence of the therapy on Apgar score, onset of symptomes and haematologic status, necessity of assisted ventilation and neonatal mortality. RESULTS: We found a significant decrease in the incidence of RDS (40%), severity of vital life-threatening distress and neonatal mortality (60%). There were no significant side effects for the babies treated versus untreated. CONCLUSIONS: Antenatal steroids given to the mother in imminence of premature birth are for real benefit in reducing neonatal mortality, increasing the number of survivors among small prematures and improving their quality of life. Even life threatening distress from other causes seem to be less severe, and even an incomplete course therapy conduces to decrease of distress severity.

Anti-Inflammatory Agents↗

PubMedDate not supplied

[Radiological findings in distal radius fractures].

X-ray examination in distal radius fractures is very important for the management and prognostic of these fractures. Anterior and lateral radiographs must be taken in standardised position to avoid errors in measurements. On antero-posterior x-ray of the distal radius the important parameters are: radial length (N = 11-12 mm), radial angle (N = 22 degrees-25 degrees) and radial width. For the radial length three methods of measurements (Gartland, Gelberman and Palmer) are presented. On the lateral x-ray the palmar inclination of the distal radius may be measured (N = 10 degrees-12 degrees). Modifications of these parameters associated with distal radius fractures are presented.

Humans↗

PubMedDate not supplied

[White-Bland-Garland syndrome: the maximum natural development of the coronary anastomosis(II)].

The anomalous origin of the left coronary artery from pulmonary artery (White-Bland-Garland syndrome) is a very rare coronary malformation, having despite the great mortality in the early childhood, an adult form, characterized by minor symptoms and long course. This paradoxical situation is totally dependent to the complete development of the coronary anastomosis, allowing the right coronary flow to perfuse the left myocardium. The theory of the "terminal arterial perfusion" of the heart, still persistent in some monographs is meeting in this natural situation its strongest opponent argumentation. The coronary anastomosis, clearly visible by coronarography are large enough (in late stages) to inverse the flow in left coronary artery, filling the pulmonary artery. Is the coronary-pulmonary shunt, responsible for the majority of symptoms, in the 5th or 6th decades. The adult form of the White-Bland-Garland syndrome is indicative for the maximum result we may hope to reach using the new revascularisation method for ischemic heart disease: new vessels formation and enhancing the coronary anastomosis by growth factors administration therapy.

Coronary Artery Bypass↗

PubMedDate not supplied

[Small renal cell carcinoma- an update and management].

The detection of small renal cell carcinomas has increased after the introduction of ultrasonography (US) and computed tomography (CT) in the current practice. Their early detection has been extremely important for therapy and prognosis but has opened new diagnostic problems including differential diagnosis, surgical or non-surgical management and imaging follow-up. Small renal carcinomas can be either solitary or multiple, synchronous or metachronous. A synthetic review of incidence, clinical findings, imaging modalities and differential diagnosis of the small renal cell carcinoma will be presented.

Carcinoma, Renal Cell↗

PubMedDate not supplied

[Phenytoin influence on human metanephros].

The influence of Phenytoin on the human embryo is knowing to produce the fetal hydantoin syndrome. Even this syndrome is knowing to produce microcephaly, mental retardation, eyelid ptosis etc it is not mentioned the influence of Phenytoin on the human metanephros. This is the reason of our study, made on human embryos. Their mothers received during pregnancy Phenytoin. In one studied embryo we have remarked a malformation in the metanephros. Even we can not make a strong correlation between the malformation and the Phenytoin we consider that pregnant women should not use Phenytoin during pregnancy.

Adult↗

PubMedDate not supplied

[Anatomic and physiopathologic basis for the diagnosis and treatment of intestinal ischemia].

Changes of circulatory parameters in splanchnic territory lead to gut ischemia in an acute or chronic form (postprandial abdominal stroke). The implicated factors in intestinal ischemia are the timing and kind of onset, countercurrent vascularization and the eventuality of anastomotic subsystems for becoming hypertrophic. Superior mesenteric artery (SMA) is the "key" blood vessel implicated in the production of chronic intestinal ischemia, the atherosclerotic lesion being localized more frequent near SMA's ostium or even at ostium itself. Nonoclusif ischemia is induced by another stimulus that provokes mesenteric vasoconstriction, status that affects more the antimesenteric intestinal border, with a larger expansion at mucosa level. The most reseed diagnostic methods are selective angiographies and ultrasound examination. Usually chronic intestinal ischemia is clinically asymptomatic and becomes clinical evident just in the presence of an acute superposed factor or when at least two digestive arteries are affected. Revascularization methods are different, based on the type, mechanism and site of obstruction, each with its advantages and disadvantages. The most used method is retrograde aortomesenteric by-pass, at infrarenal aortic level (that is more accessible than the supraceliac aorta) and SMA reimplantation.

Humans↗

PubMedDate not supplied

[Correlations between the type of distribution of the branches of the inferior mesenteric artery and the aspect of the mesocolon].

Emergence pattern of inferior mesenteric artery (IMA) branches leaded to description of 6 types of arterial distribution, each of them being correlated with a certain mesocolon aspect. The height of mesosigmoid depends on coalescence pattern and grade, and has a particular importance in terminal colic and retroperitoneal viscera's surgery. For each of the 6 types of distribution are described different ways of differential ligatures, for elongation and descending the colon, initially establishing the predominant collateral trunks. For practicing these ligatures we have to take count of preoperative paraclinic investigations, general and particular haemodynamic conditions and some intraoperatory parameters.

Anastomosis, Surgical↗

PubMedDate not supplied

[Anatomical and surgical considerations concerning the segmentation of the pancreas].

Pancreatic vascularization, especially the right segment (the head of the pancreas) has great surgical importance, due to its anatomical variety. From this practical point of view, establishing the type of the patient's pancreatic vascular pattern is highly recommended not just diagnosis purposes, but especially for its indispensable role in surgical decision. Selecting the appropriate technique, based on the imagistic evidences must consider the anatomical studies, which propose a systematic vision of the cephalic area vascularization, detecting two major types of arterial distribution. The first type is especially anastomotic; meanwhile the second one is terminal, these two varieties leading to a different surgical technique, best adapted for avoiding hemorrhages or ischemic necroses. Between the classic two segments of the pancreas (cephalic and caudal parts) there is a less vascularized area, which includes just an intersegmentary artery and the pancreatic duct, surgically sectioned during the separation operation of the two pancreatic segments. Vascular variety of the pancreas may be related to both embryological development of the pancreatic tissue, and that of the abdominal aortic branches.

Humans↗

PubMedDate not supplied

[Staging and diagnosis in accidental hypothermia].

Core body temperature below 35 degrees C is defining arbitrarily hypothermia. There is no worldwide consensus concerning the staging and resuscitation strategies in such a vital emergency, not even in rewarming strategy. Accidental hypothermia has its own "survival chain", modifying some steps or the timing in the common cardiopulmonary resuscitation protocol, according to some particularities of the metabolism in such an accident. Taking into account the two major events during hypothermic conditions (ventricular fibrillation and coma), we have proposed a better borderline between the three severity classes, based on clinical, paraclinical and prognostic arguments. The interest in this special environmental emergency situation is coming not only from its incidence, but especially from its particular long time period in which the resuscitation maneuvers could be effective, so that a literature review mixed with our practical observations may be of didactical and legal benefit also.

Cardiopulmonary Resuscitation↗