[Ruptures of the rotator cuff. Results and perspectives of the retrostructure (author's transl)].
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Biomedical subjects
Publications and source records attributed to D Patte.
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Blood pressure regulation was studied in nine patients with tetraplegia following total cervical section. Ten minutes after placing the patients in an inclined position at 30 degrees there was a marked reduction in blood pressure, an increase in heart rate, and absence of increased peripheral resistance. Valsalva's maneuver was pathological in all cases (lack of overshoot). Circulating catecholamines were measured in five cases and were low in decubitus and did not react to orthostatism. Plasma renin and aldosterone levels were at the upper limits of normal and reacted strongly to orthostatism. Marked hypersensitivity to exogenous angiotensin and noradrenaline was observed in all cases. These modifications result from section of the sympathetic efferent pathways. High plasma renin levels and their increase during orthostatism are not incompatible with these findings and probably result from intervention of renal baroreceptors. Whatever the mechanism involved, this increase in plasma renin activity could play an important role in the control of blood pressure in tetraplegic patients.
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In spite of its clinical features, the diagnosis of posterior dislocation of the shoulder is often missed. The authors considered that this is due to an inadequate analysis of the x-rays. They show that the diagnosis can be made on an antero-posterior x-ray and describe the findings in fourteen cases. They note a modification of the gleno-humera line and the features of the associated impaction fracture. A lateral view is necessary to make the diagnosis certain, an axillary view being preferred to a trans-thoracic late-femoral head or of the posterior glenoid margin.
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In a patient with occupational plumbism and a normal kidney function, EDTA therapy (1 g/24 h) resulted in a massive lead excretion (15 000 microgram/24 h) together with acute renal failure. A direct nephrotoxic effect of EDTA was excluded: after renal function returned to normal, EDTA could be subsequently readministered at progressively increasing doses (250 mg to 1 g/24 h) without any renal dysfunction. These findings strongly suggest a close relationship between the burden of lead mobilized by EDTA and the acute renal failure. This case can be classified as acute lead nephropathy of which only a few instances have been reported in the literature. The interest of monitoring lead excretion during chelation therapy is particularly emphasized.
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The authors report a new observation of Goodpasture's syndrome in a 21 years old patient. Diagnosis was made by renal biopsy after discovering, by immunofluorescence techniques, linear deposits of IgG and C3 on the renal basal lamina. Anti-basal lamina antibodies of the plasma were not found. In spite of therapy by steroids, a rapid worsening of renal functions accompanied a nephrotic syndrome. Supplementing hemodialysis helped patients to survive without recurrence of hemoptysis. Heparinotherapy prescribed on the creation of an arteriovenous fistula seemed to have brought a temporary improvement of the renal function.
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