[Mannosidosis. A clinical case].
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Biomedical subjects
Publications and source records attributed to D Pedrola Guixe.
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A total of 100 clinical records have been studied to as certain the diagnostic use of brain CT. Most frequent diagnoses are: hypoxic-ischemic encephalopaty, seizure disorders, psychomotor delay, head enlargement and trauma. The first years of life was the period with a higher frequency of applications and the greater percentage of pathologic results (75-80 por 100) was found among intracranial hypertension, fetal distress, macrocephaly or infections of Central Nervous System and their sequelae. Minus than 50 por 100 of CT scans requested for seizures, psychomotor delay and trauma demonstrated true abnormal findings. Nearly half (53 por 100) of exams were pathological and 87 por 100 of them were useful to confirm or complete the diagnosis. It is possible to predict an increase in the number of examinations to perform in the future, although it many be replaced by alternative techniques.
The authors have realized a retrospective study over 100 patients affected by cerebral palsy and selected at random. Various parameters have been examined, especially the incidence of epilepsy and its relations with electroencephalographic (EEG) alterations. The conclusion is that epilepsy appears in more than 50% of the patients and is quite always accompanied by EEG alterations. Its appearance is precocious, usually no more than 4 years after the beginning of the illness, and worsens the intellectual deterioration which is usual in these patients. A precocious and prolonged treatment yields very advantageous results in more than 50% of the patients and important improvements in 21% of them. No results were obtained in the 15%.