PubMed Health⌕ Search

Biomedical subjects

D Perrot

Publications and source records attributed to D Perrot.

40 records · Page 3Linked to original sources

[Evaluation of nutritional status in hospital surgical patients (author's transl)].

The nutritional status of 90 hospital surgical patients was evaluated on admission by simple, easily measured anthropometric and biological indexes. The results indicated that many patients were admitted with malnutrition, the degree of which varied according to the indices utilized. Anthropometric measurements showed that 29 to 35% of the patients had moderate malnutrition and 0 to 18% severe malnutrition, while biological indexes revealed moderate or severe malnutrition in over 50% of the subjects. Changes in indices were assessed in 51 patients during their stay in hospital. There was a significant decrease in all anthropometric indexes (p less than 0.01) and in blood albumin (p less than 1.10(-6)) though not in other biological indexes. Differences in sensitivity between indexes may be due to the fact that they reflect activities in different tissues. Several indexes must therefore be utilized in hospital patients to make detection and monitoring of malnutrition more reliable and to evaluate its various aspects.

Adult↗

[Deliberate self-overdose with propranolol. Changes in serum levels (author's transl)].

Suicidal attempt using beta-blockers are rare. Overdose by the ingestion of a large number of tablets rarely exceeds the high therapeutic doses suggested for the treatment of certain resistant cases of hypertension. The case described is that of a 65-year-old patient who took 800 mg of propanolol. Observation of plama levels showed that the half-life propanolol in the case of overdose is prolonged: 8.6 hours in this case, with a maximum plasma level of 1536 ng/ml. Plasma renin activity levels were low during the phase of intoxication and showed evidence of a rebound effect at its end. Treatment is above all that of the circulatory insufficiency produced: isopropylnoradrenaline or glucagon. Indications for extra-renal dialysis should take into account knowledge concerning the pharmacokinetics of these drugs and their prolonged physiological action.

Aged↗