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Biomedical subjects

D Petry

Publications and source records attributed to D Petry.

10 recordsLinked to original sources
PubMed2001

[Rehabilitation protocols after repairs of zone 2 of the flexor tendon of the hand: presentation and indications].

We report the results of a retrospective study of 47 adult patients corresponding to 54 fingers, operated on in the emergency room at Nancy University Hospital between December 1996 and October 1998. These patients were managed using three different postoperative therapy protocols: passive mobilisation according to the Duran technique, active-passive mobilisation according to the Kleinert technique and immediate active mobilisation as described by Strickland. Patients were evaluated in three different ways; active range of movement obtained according to the Strickland scale, the "400 points" flexor function test and the delay in returning to work. Combining all three evaluations showed a 65% rate of satisfactory results, 22% fair and bad results and 13% ruptures. Analysis according to the re-education technique showed a strong superiority of the Strickland protocol. This now needs to be confirmed by a more extensive prospective study. Delay before return to work is not affected by the type or re-education technique chosen, but side-effects are less frequent with the Strickland method. A result in terms of range of active movement alone did not fully evaluate the result of a flexor tendon repair: functional testing was better at this end and the global "400" points test score gave more useful information than each of its component tests taken individually (Purdue pegboard, Minnesota test, Box and Block). Functional testing seemed more helpful in guiding the medical team in its treatment strategy.

Adult↗
PubMed2001

A comparative clinical and electromyographic study of median and ulnar nerve injuries at the wrist in children and adults.

The outcome of 38 median and ulnar nerve injuries at the wrist in 15 adults and 15 children were studied with a follow-up of at least 1 year. Each patient was assessed clinically and with nerve conduction studies. The results confirm a markedly superior sensory recovery in children. However the children had persistent motor deficiencies. This difference in the clinical results of adults and children was not reflected in the nerve conduction results which were similar in both groups.

Adolescent↗
PubMed2001

A comparison between clinical results and electromyographic analysis after median or ulnar nerve injuries in children's wrists.

The purpose of this study was to analyze the results of median or ulnar nerve transections to the wrist in 14 children between 1994 and 1999. On sustaining their injury, all patients underwent treatment at the University Hospital of Nancy. They were all seen afterward for clinical and electromyographic evaluations. The clinical examination was mainly to judge the quality of sensory recovery, using the Weber and Dellon tests, as well as motor recovery. Electromyographic examination of the motor and sensory tissues was carried out systematically on each patient. The analysis of these results highlights discordance between the quality of the clinical results and nerve regrowth identified via electromyography. Good nerve regrowth does not necessarily mean a good sensory recovery.

Adolescent↗
PubMed1996

[Unidimensionality of a functional measure for patient with an injured upper limb].

The construction of an instrument including a number of tests requires an analysis of its structure and its unidimensionality (which allows calculation of global score), and the determination of the difficulty level of various tests. This study examined a tool including 67 tests designed to evaluate the functional ability of patients with an injured upper limb. The patients seen in a rehabilitation centre during 12 months (173 subjects) were evaluated by the occupational therapists familiar with the tool. The statistical analyses were made using the principal component analysis method (PCAM), the Cronbach's coefficient and the Rasch model. The PCAM showed 3 principal factors which explained 44%, 10% and 4% of the total variance respectively in the case of patients with injured dominant limb. The predominance of the first axis and the high ratio of first by second eigenvalues suggested the unidimensionality of the tool. The Cronbach's value of 0.97 attested the good congruence of the items. The results obtained with the Rasch model seemed to be consistent with the hypothesis of the unidimensionality of the tool. This analysis also provided the difficulty scale of various tests. Similar results were obtained in patients with injured non dominant limb or with all the sample. The methods used provide complementary results.

Activities of Daily Living↗
PubMed1994

Experimental and clinical study of the effect of naftidrofuryl on the recovery from peripheral nerve lesions.

After primary repair of lesions of nerves and vessels, patients who were administered a vasoactive drug, naftidrofuryl, postoperatively, had a better functional recovery than untreated patients. Evidence for the favourable effect of the drug on nerve regeneration was first obtained from experiments in the rat. The sciatic nerve was transected and repaired with standard microsurgical techniques. Results were evaluated by electromyography and histology. Data indicated that treated animals had better motor responses and distal latency than untreated rats. Fibre counts showed a greater number of nerve fibres in the distal stump of treated animals. The clinical study was undertaken in cases of carpal tunnel syndrome with muscle atrophy. Assessment was performed by electrophysiology: motor and sensory conduction was studied. Data showed that all treated patients recovered totally or partially from the thenar atrophy they presented before operation, whereas thenar atrophy persisted in 37% of the patients receiving placebo. In conclusion, naftidrofuryl has an experimentally and clinically favourable effect on nerve regeneration and on muscle trophicity, but the mechanism of action of this drug is not known.

Aged↗
PubMed1989

Primary repair of extensor tendons with assisted post-operative mobilisation. A series of 48 cases.

Forty-eight patients with lesions of the extensor apparatus of the hand were treated by primary repair with assisted post operative mobilisation by means of a dynamic extension, low profile splint. They were divided into three groups: 25 simple wounds of the extensor tendons of the fingers; 14 simple wounds of the extensor tendon of the thumb; 9 complex lesions. The mobility of the tendinous suture and the callus displacement were monitored by means of metallic markers implanted at operation. Functional electromyographic study during physiotherapy permitted refinement of the technique of reeducation by a limitation of the range of flexion of the proximal interphalangeal articulations. The results are divided into 4 categories: excellent 33 (60%), good 9 (16.4%), average 4 (7.3%), bad 9 (16.4%). No complications (infection, loosening of suture, reflex sympathetic dystrophy) were detected in this short preliminary series. The proposed technique produced improvement of only minor significance in comparison with traditional methods, when applied to uncomplicated wounds. Significantly improved results were obtained in the group of patients with complex lesions.

Adult↗
PubMed1983

Fascicular nerve graft using an empty perineurial tube: an experimental study in the rabbit.

An experimental model of a free, empty perineurial tube for use as a nerve graft is presented as an alternative to existing methods. The technique is described and the model compared with conventional nerve graft in the sciatic nerve of a rabbit. Results are evaluated with EMG studies, angiography, and histology. The experimental model compared favorably with the standard graft. Further avenues of investigation and clinical use are suggested.

Angiography↗
PubMed1983

The effect on neutral gene flow of selection at a linked locus.

The effect on gene flow at a neutral locus of a selective cline at a linked locus is investigated. A diffusion approximation for a two-locus island model is derived in which only one locus is subject to selection. The moments of the stationary distribution are obtained and compared to the corresponding moments from a one-locus, neutral island model. This comparison yields an effective migration rate. The effective migration rate is always less than the actual migration rate, but this effect is seen to be small for weak selection and loose linkage in the case of adult migration. The importance of selection at linked loci to the question of genetic differentiation in a subdivided population is discussed.

Animals↗
PubMed1980

Density-dependent selection in a random environment: An evolutionary process that can maintain stable population dynamics.

A theoretical analysis of natural selection is presented in which fitnesses depend on population density and randomly varying environmental processes. The theory is based on a general, heuristic analysis of a pair of coupled, nonlinear, stochastic difference equations that describe the joint dynamics of allele frequencies and population size. Four main conclusions emerge from the investigation of a particular class of models: (i) growth rates at low population densities tend to increase; (ii) individual selection, given sufficient genetic flexibility, will mold growth rates at higher densities so that in spite of i, stable deterministic population dynamics are maintained; (iii) "more fit" genotypes cannot be simply characterized-in particular, the mean population size need not be increased; and (iv) genetic polymorphisms can be maintained in both haploid and diploid organisms.

Journal Article↗