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Biomedical subjects

D Picus

Publications and source records attributed to D Picus.

At least 55 records · Page 3Linked to original sources

Delayed rupture of a pseudoaneurysm of the costocervical trunk: treatment with therapeutic embolization.

Fourteen days after removal of an internal jugular catheter inserted prior to renal transplantation, a patient presented with brisk arterial hemorrhage from the insertion site. The hemorrhage, caused by a ruptured pseudoaneurysm of the costocervical trunk, was controlled by transcatheter embolization with gelatin particles. One year later the patient reported no problems related to the pseudoaneurysm or its management.

Aneurysm↗

Angiography is useful in detecting the source of chronic gastrointestinal bleeding of obscure origin.

The treatment of patients with chronic gastrointestinal bleeding can be a frustrating diagnostic challenge. In the past 10-15 years, a variety of new diagnostic procedures (e.g., fiber-optic endoscopy, scintigraphy, and double-contrast barium studies) have become available to examine these patients. Despite these new procedures, a small number of patients continue to bleed without a defined cause. We sought to evaluate the role of visceral angiography in patients with chronic gastrointestinal bleeding in whom findings on an extensive noninvasive workup have been normal. Between 1983 and 1990, we obtained angiograms on 36 such patients. The cause of bleeding was established by angiography in 16 patients (44%). In 11 of these 16, angiography revealed only a structural abnormality without active bleeding. Twenty patients had normal angiographic findings. No angiograms were false-positive, but three were false-negative (8%). No complication occurred as a result of the angiographic procedures. Our experience shows that visceral angiography can provide a positive diagnosis in a significant number of patients with chronic gastrointestinal bleeding of obscure origin in whom all other diagnostic measures have been unrevealing. Despite improvements in noninvasive diagnostic techniques, angiography still remains an important tool for examining this group of patients.

Adult↗

The importance of preoperative evaluation of the subclavian vein in dialysis access planning.

Adequate venous outflow is critical to the proper function of a vascular-access graft (arteriovenous fistula) used for chronic hemodialysis. Stenosis of the subclavian vein can significantly compromise this venous outflow. The development of such subclavian vein stenoses has been associated with the prior placement of temporary subclavian vein dialysis catheters. We evaluated the importance of preoperative detection of these stenoses before placement of a permanent vascular-access graft in the upper extremity. Upper extremity venography was performed before placement of a permanent vascular-access graft in 43 patients. A total of 62 extremities were evaluated. A 40% prevalence of moderate or severe subclavian vein stenosis was found in patients with prior or existing temporary dialysis catheters in the subclavian vein. No stenoses were found in patients without a history of dialysis catheters in the subclavian vein. This difference in the prevalence of subclavian vein stenosis is statistically significant (p less than .001). In no case was the stenosis suspected clinically. Before placement of a permanent vascular-access graft, the subclavian vein should be evaluated in all patients with a history of a temporary dialysis catheter in the subclavian vein. The use of sites other than the subclavian vein for temporary dialysis is strongly encouraged.

Arteriovenous Shunt, Surgical↗

Prevalence of local venous thrombosis after transfemoral placement of a Bird's Nest vena caval filter.

Bird's Nest vena caval filters were placed in 63 patients over a 6-month period by means of a transfemoral (n = 62) or transjugular (n = 1) approach. To determine the prevalence of access-site thrombosis, compression color Doppler flow imaging was performed 1-11 days after the procedure in 48 patients without suspected or documented preexisting thrombus. Clinical follow-up was from 5 to 289 days (mean, 100 days). Findings at ultrasound (US) examination were normal in 38 patients, and all of these patients remained clinically asymptomatic. Nonocclusive thrombus was seen in nine patients, eight of whom remained asymptomatic. A single patient had an occlusive thrombus at US. This patient had leg swelling. Nonocclusive thrombus did not predispose patients to the development of clinically evident occlusive thrombosis. The authors conclude that the transfemoral placement of the Bird's Nest vena caval filter is associated with a low prevalence (2%) of femoral vein occlusion documented at US follow-up. This contrasts with results from a similarly designed study demonstrating a 17% prevalence after percutaneous Greenfield filter placement.

Adult↗

Choledochoscopic stone removal through a T-tube tract: experience in 75 consecutive patients.

Retained biliary stones remain a common clinical problem in patients after surgery. Since 1984, the authors have used choledochoscopy in the treatment of suspected retained biliary stones in 75 patients. These procedures were performed in the radiology department with use of local anesthesia supplemented by an intravenously administered sedative and analgesic. A 15-F flexible fiberoptic choledochoscope was used. Fifty-one of the 75 patients were treated as outpatients. Treatment was successful in 74 of 75 patients; in one patient, intrahepatic stones were not completely removed. Electrohydraulic lithotripsy was used to fragment calculi in 11 patients (15%). Biopsies were performed in four patients (5%). Five minor complications occurred; three required overnight admission. Choledochoscopic-assisted removal of retained biliary calculi is a highly effective and safe procedure. Advantages over standard fluoroscopic stone removal include the ability to directly visualize and fragment adherent or impacted stones and visualize noncalculous filling defects, such as air bubbles, mucus, and biliary tumors.

Adult↗

Optimization of high-efficiency hemodialysis by detection and correction of fistula dysfunction.

Recirculation studies were performed in 103 patients treated with high-efficiency dialysis over a 14 month period. Fistulograms were performed on 22 out of 25 patients with greater than 0.15 fractional recirculation at a 400 ml/minute blood pump setting. Clinically significant abnormalities were found in 82% (N = 18) and treated in 17. Two patients had second episodes of elevated recirculations and were treated again within the period of follow-up. Treatment with angioplasty (N = 11) or surgical revision (N = 8) resulted in a fall in recirculation from 0.33 +/- 0.04 to 0.12 +/- 0.02 (P = 0.001). The fractional reduction of urea clearance due to recirculation fell from 0.20 +/- 0.03 to 0.08 +/- 0.02 (P = 0.001) and the effective urea clearance of the dialysis treatment rose by 16% from 193 +/- 7 ml/min to 224 +/- 6 ml/min (P = 0.001). Pre-dialysis BUN fell from 72 +/- 4 mg/100 ml to 62 +/- 3 mg/100 ml (P = 0.012). There was no correlation between venous pressure (VP) at 400 ml/min blood pump setting and recirculation (R2 = 0.04), although VP changed significantly comparing values before and after fistula repair (211 +/- 10 vs. 186 +/- 7 mm Hg, P = 0.012). Venous pressures in 20 of the patients in our dialysis unit with recirculations of less than 0.10 were 201 +/- 6 mm Hg (P = NS compared to patients with recirculation greater than or equal to 0.15 at 400 ml/min blood flow).(ABSTRACT TRUNCATED AT 250 WORDS)

Arteriovenous Shunt, Surgical↗

Massive arterial hemorrhage from the stomach and lower esophagus: impact of embolotherapy on survival.

The authors retrospectively reviewed the clinical courses in 36 patients referred for angiographic evaluation of massive arterial hemorrhage from the stomach, gastroesophageal junction, and lower esophagus. Twenty-four patients underwent embolotherapy, and 12 were treated with nontranscatheter therapy such as surgery, Sengstaken-Blakemore tube placement, endoscopic submucosal injection of epinephrine, or supportive medical therapy. Bleeding was controlled completely in 15 (62%) and partially in three (13%) of the patients who underwent embolotherapy. In nine of the patients treated with nontranscatheter therapy (75%), bleeding control was complete. Sixteen patients died, including seven of 28 in whom bleeding was controlled. There was no significant difference in the mortality rates of patients treated with nontranscatheter therapy (46% and 42%, respectively). Survival correlated with the clinical condition at the time of intervention. All patients with multiorgan failure died, while 87% of the other patients, even those with serious cardiovascular compromise, survived. The results imply that massive gastric hemorrhage should be treated aggressively, before it results in multiorgan failure.

Acute Disease↗

Fluoroscopically guided percutaneous gastrostomy and gastroenterostomy: analysis of 158 consecutive cases.

We reviewed our experience with 158 consecutive patients who underwent either percutaneous gastrostomy or percutaneous gastroenterostomy during a 2-year period. The catheters used included Foley catheters (36), Cope-type gastric catheters (86), or Carey-Alzate-Coons gastrojejunostomy catheters (36). Gastrojejunostomy tubes were placed in patients with gastroesophageal reflux or aspiration, gastric atony, or partial gastric obstruction. Ninety percent of the tubes were placed for feeding purposes. The technical success rate was 100%. Thirty-day follow-up was obtained in 89%. Thirty-day mortality was 26%, reflecting the substantial number of debilitated patients. No deaths were directly related to tube placement. Major morbidity was 6% and included hemorrhage, peritonitis, tube migration, and sepsis. Minor morbidity was 12%. There was no difference in 30-day mortality or feeding tolerance between the tube types (p less than .05). Patients with Foley catheters had more complications necessitating surgical intervention and an increased incidence of tube changes required within 30 days. These were the only statistically significant differences between the tubes (p less than .05). Our results show that percutaneous gastrostomy is a safe and effective means of gastroenteric feeding or decompression. Because of the fewer complications and ease of insertion, the Cope type of gastrostomy tube has become our preferred catheter for percutaneous feeding or decompression.

Aged↗

Intracorporeal biliary lithotripsy.

Most bile duct calculi can be removed with standard percutaneous or endoscopic techniques. Very large stones are the most common cause for failure. Intracorporeal lithotripsy, and EHL in particular, can be used safely in either the biliary tree or gallbladder to fragment these large stones and allow percutaneous removal or passage. Intracorporeal EHL requires direct vision to prevent damage to the bile duct mucosa. Intracorporeal laser lithotripsy may offer some safety advantages, but the laser requires much more expensive equipment than intracorporeal EHL. Additional studies are needed to determine the technique that is better in each circumstance.

Cholangiography↗

Role of percutaneous intracorporeal electrohydraulic lithotripsy in the treatment of biliary tract calculi. Work in progress.

Although surgery is the treatment of choice for symptomatic gallstones, most bile duct calculi can be successfully treated with the use of routine percutaneous or endoscopic methods. Failure of these methods is most often associated with stones larger than 1.5 cm. The authors used percutaneous intracorporeal electrohydraulic lithotripsy (EHL) to treat 11 patients with calculi in the bile ducts (n = 10) or gallbladder (n = 1) in whom the use of other percutaneous or endoscopic methods failed. The stones in all 11 patients were successfully fragmented and removed. There were no complications. Intracorporeal EHL is an effective alternative therapy for the treatment of biliary tract calculi when standard methods fail.

Aged↗

Detection of focal hepatic masses: prospective evaluation with CT, delayed CT, CT during arterial portography, and MR imaging.

The sensitivities of contrast medium-enhanced computed tomography (CT), delayed CT (DCT), CT during arterial portography (CTAP), and magnetic resonance (MR) imaging for detecting focal liver lesions were prospectively evaluated in eight patients who subsequently underwent hepatic lobectomy or transplantation. Pathologic evaluation of the resected liver specimens demonstrated 37 lesions. The sensitivities were 81% (30 of 37 lesions) for CTAP, 57% (21 of 37 lesions) for MR imaging, 52% (12 of 23 lesions) for DCT, and 38% (14 of 37 lesions) for contrast-enhanced CT. The difference between the sensitivity of CTAP and the sensitivities of the other imaging tests was statistically significant (P less than .004). Of the lesions smaller than 1 cm in diameter, CTAP depicted 61% (11 of 18 lesions), MR imaging 17% (three of 18 lesions), CT 0% (zero of 18 lesions), and DCT 0% (zero of nine lesions). It is concluded that for preoperative detection of focal hepatic masses, CTAP is the most accurate technique available to most radiologists. Patients with primary or secondary hepatic neoplasms who are being considered for hepatic resection should undergo CTAP as part of their preoperative examination.

Adult↗

Percutaneous cholecystolithotomy: preliminary experience and technical considerations.

Surgical cholecystectomy is associated with a high morbidity and mortality in elderly patients with acute calculous cholecystitis and underlying cardiac or pulmonary disease. Currently there are few alternatives for treating these patients. The authors have used percutaneous cholecystolithotomy in 11 such high-risk patients for definitive treatment of gallbladder calculi. In all 11 patients all stones were successfully removed from the gallbladder and cystic duct. The entire procedure--from initial tube placement to final tube removal--lasted 17-40 days (mean, 21 days). There were two complications: one minor--local wound infection--and one major--bile peritonitis with eventual death. Percutaneous cholecystolithotomy is an effective alternative therapy for acute calculous cholecystitis in elderly, debilitated patients.

Aged↗

Chronic intestinal obstruction: value of percutaneous gastrostomy tube placement.

Percutaneous gastrostomy tubes were placed in six patients for treatment of nausea and vomiting associated with chronic intestinal obstruction. There were no complications related to the tubes, and in all patient, symptoms were relieved. For the patient, the advantages of gastrostomy over nasogastric drainage include improved comfort, increased mobility, and a decreased risk of pulmonary aspiration. Percutaneous gastrostomy is a safe procedure and provides excellent palliation for intractable nausea and vomiting in patients with chronic intestinal obstruction.

Adult↗

Use of digital subtraction angiography for evaluation of vascular access for hemodialysis.

We used digital subtraction angiography (DSA) with conventional methods of contrast injection to evaluate 13 failing vascular accesses in 12 patients undergoing hemodialysis. DSA results were confirmed in all cases by surgical findings and/or clinical follow-up. The DSA technique is extremely flexible and rapid and requires the injection of only small amounts of dilute contrast with much less patient discomfort. DSA is an excellent alternative to film screen angiography for the evaluation of vascular access complications.

Angiography↗