Biomedical subjects
D Potyk
Publications and source records attributed to D Potyk.
Comparing two formats for clinical "pearls" at morning report.
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Management of gastrointestinal lymphoma.
A study was made of 65 patients with primary gastrointestinal (GI) lymphoma. The occurrence was 40 (62%) in stomach, 15 (23%) in the small intestine, and 10 (15%) in colorectum. The majority of patients had their histology classified according to Rappaport's classification. Diffuse histiocytic type had the worst prognosis (median survival 13.8 months), and nodular histology had the best prognosis. A modified staging system proposed by Blackledge et al. was used. Patients who had their disease confined to one viscus (Stage I) or with spread to regional lymph nodes (Stage II) had an excellent prognosis, with a 5-year survival of 87 and 67%, respectively. However, those who had distant nodal involvement (Stage III, e.g., para-aortic nodes) or spread to adjacent organs within the abdomen (Stage IV) had worse prognosis, with 5-year survival of 40 and 13%, respectively. In Stage I, radiotherapy alone was as effective as surgical resection. None of the 11 patients treated by radiotherapy alone had perforation or bleeding. The 5-year disease-free survival was 51%.
Intestinal obstruction from impacted antacid tablets.
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Preoperative cardiac evaluation for elective noncardiac surgery.
We reviewed the approach to preoperative cardiac risk assessment, incorporating new information regarding the pathophysiologic features of perioperative myocardial ischemia and recent clinical trials. Relevant articles were identified from a MEDLINE search, followed by bibliography review of the articles identified. The multifactorial risk indexes are valuable in stratifying risks among unselected patients undergoing noncardiac surgery, but they underestimate the risks in selected groups, particularly patients with peripheral vascular disease. The preoperative evaluation of patients with coronary artery disease and risk reduction strategies for high-risk patients are considered. There are no prospective randomized clinical data comparing preoperative revascularization to intensive medical therapy and clinical decisions must be individualized. Risks particular to patients with congestive heart failure and valvular heart disease are also reviewed. Patients with congestive heart failure can undergo noncardiac surgery safely, if their cardiac disease is well-compensated. Patients with aortic stenosis have high risks, and management strategies include valve replacement, aortic valvuloplasty, and aggressive medical treatment. These modalities have not been compared prospectively, and clinical decisions must be individualized. Preoperative arrhythmias are important risk factors, although they appear to confer risk only when due to underlying heart disease. A thorough, targeted history and physical examination supplemented with judicious laboratory studies are usually sufficient to assess a patient's risk for upcoming noncardiac surgery. The clinical history should identify risk factors that predict cardiac complications, and special attention should be given to those risk factors that can be modified before surgery. New developments in perioperative medicine will likely lead to postoperative interventions to reduce silent myocardial ischemia and clinical complications.
Diabetes insipidus: an unusual cause of urinary frequency during pregnancy.
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