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Biomedical subjects

D Puppin

Publications and source records attributed to D Puppin.

13 recordsLinked to original sources
PubMed1993

Amplified surface microscopy. Preliminary evaluation of a 400-fold magnification in the surface microscopy of cutaneous melanocytic lesions.

BACKGROUND: Surface microscopy (SM) opened a new dimension in the clinical assessment of cutaneous pigmented lesions. Diagnostic patterns were described to provide guidelines for the preoperative diagnosis of pigmented skin lesions. OBJECTIVE: Our purpose was to explore whether "amplified" surface microscopy (ASM), by increasing magnification up to 400-fold, provides any improvement in the analysis of patterns previously described in cutaneous pigmented lesions. METHODS: A fiber-optic camera, allowing magnification up to 400 times and associated with an imaging system computer, was used for the analysis of 40 melanocytic lesions. Special emphasis was put on the most important features that can be observed in surface microscopy, the so-called pigment network and brown globules. RESULTS: The lines (grids) of the pigment network appeared to be composed of three zones: two darker external lines and one central clearer zone. This pattern, not previously seen with SM, is compatible with the anatomy of pigment accumulation in the epidermal rete ridges. Two types of brown globules could be distinguished: one located in the center of the pigment network holes, the other on the lines of its grids. The "on-the-grid" type was smaller than the "in-the-hole" type; it could be misinterpreted as "black dots" when seen at lower magnification (x10). CONCLUSION: ASM is a tedious procedure that may help in the analysis of the features previously recognized by SM; SM is more accessible for routine use.

Diagnosis, Differential↗
PubMed1993

[Bacillary angiomatosis. A pseudoneoplastic infection in AIDS patients].

Bacillary angiomatosis is a newly recognized pseudoneoplastic vascular disease seen in the setting of human immunodeficiency virus (HIV) infection. The disease is characterized by a cutaneous infection with reddish papules or nodules that are similar to pyogenic granulomas or Kaposi's sarcoma in clinical appearance. It is caused by the mildly gram-negative bacillus Rochalimaea henselae, which can be identified in tissue sections by means of Warthin-Starry stain. The historical, clinical, histopathological, and microbiological aspects and the differential diagnosis and therapy of bacillary angiomatosis are reviewed. It is important to be aware of these characteristics, because these lesions can easily be treated with antibiotic therapy.

AIDS-Related Opportunistic Infections↗
PubMed1992

[Controversial aspects of stage I skin melanomas].

Melanoma is still the most frequent cause of death for diseases arising in the skin. The mortality rate is approximately 25%, tumor thickness, sex and localization being the most important prognostic factors. It is still unclear whether the margin of excision, type of anaesthesia and the pattern of follow-up should be taken into consideration in relation to the individual prognostic groups.

Anesthesia↗
PubMed1992

Hereditary benign telangiectasia: two case reports.

We present two cases of hereditary benign telangiectasia (HBT) in which the genetic findings are compatible with an autosomal dominant hypothesis. The lesions persisted indefinitely for many years without effect on the general health of the patients. The term hereditary benign telangiectasia distinguishes the disorder from the more serious hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber). The etiology remains unknown. The condition causes only cosmetic disability and is not associated with any other diseases.

Adolescent↗
PubMed1992

Keratosis follicularis spinulosa decalvans: report of a case with ultrastructural study and unsuccessful trial of retinoids.

Keratosis follicularis spinulosa decalvans (KFSD) is a genetic disorder characterized by disseminated follicular hyperkeratosis, especially localizated to scalp and face. We report the case of a new patient displaying typical features of KFSD. Ultrastructural study was performed and displayed round keratohyalin granules in follicular keratinocytes. Trial with etretinate, which has not been reported before in this disease, proved to be ineffective.

Biopsy↗
PubMed1992

Histiocytic lymphophagocytic panniculitis (Rosai-Dorfman disease): a case report.

A 68-year-old woman presented with a symmetrical enlargement of the face and submandibular area associated with essential thrombocytosis. Biopsy of the lesions revealed a septal and lobular panniculitis disclosing a lymphohistiocytic and plasma cell proliferation with lymphophagocytosis by histiocytes, compatible with Rosai-Dorfman disease. The lesions regressed spontaneously without therapy over a period of 4 months. Diagnosis was confirmed by electron-microscopic examination and immunocytochemical presence of S-100 antigen within the histiocytic cells. A 2-year follow-up did not demonstrate any evidence of recurrence.

Aged↗