Biomedical subjects
Publications and source records attributed to D R Arora.
A total of 274 samples were collected--180 sputum samples, 82 bronchial secretions and 12 pleural aspirates. Main fungus was Candida albicans from sputum (45.5 percent), from bronchial secretions (14.6 percent). Rest were Aspergillus, Alternaria and Helminthosporium. All the pleural aspirates were negative for fungus.
Estimation of T and B lymphocytes was done in 50 patients of enteric fever, 50 duration matched non enteric fever patients and 50 normal healthy individuals. The difference in both early and late rosette forming T lymphocytes was found to be statistically significant in enteric versus non-enteric patients. Significant difference was also observed in enteric versus normal individuals in case of late rosette forming T lymphocytes.
Fine needle aspiration cytology and culture were done on 200 patients with clinical diagnosis of tuberculous lymphadenitis. Cytological changes consistent with tuberculosis were seen in 124 and 100 of these showed growth of Mycobacterium tuberculosis. Atypical mycobacteria were not isolated from any of these patients. Of the 100 culture positives, 75 were found to be positive by auramine-rhodamine and Ziehl-Neelsen staining technique. However, with the latter method the diagnosis was missed on first examination of eight smears. With periodic acid-Schiff staining mycobacteria could be visualised in 71 smears.
Tumour markers viz carcinoembryonic antigen (CEA), human chorionic gonadotrophin (HCG) in 30 cases of carcinoma breast and prostatic specific acid phosphatase (PSAP) in 30 cases of carcinoma prostate were studied by peroxidase antiperoxidase technique in paraffin blocks of tissue. Twenty three (76.7%) and 20 (66.7%) cases were positive for CEA and HCG respectively. No correlation was observed between CEA and HCG status, and histological differentiation of the tumours. All the 29 cases (100%) of adenocarcinoma prostate were PSAP positive while a single case, negative for PSAP, was of transitional cell carcinoma.
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