PubMed Health⌕ Search

Biomedical subjects

D R Ayyar

Publications and source records attributed to D R Ayyar.

41 records · Page 3Linked to original sources

Influence of height on quantitative sensory, nerve-conduction, and clinical indices of diabetic peripheral neuropathy.

We have examined associations between height and quantitative sensory, nerve-conduction, and clinical indices of diabetic peripheral neuropathy in adult diabetic patients. Vibratory sensitivity was strongly related to height when measurements were made with either the vibration sensitivity tester (P = .02) or the biothesiometer (P less than .01); however, there was no relation between thermal sensitivity (as measured with the thermal sensitivity tester) and height. The peroneal and posterior tibial motor nerve-conduction velocities were inversely related to height (P less than .05 for both). When age and diabetes duration were included as variables in multiple regression analyses, the associations with height became stronger. Clinical indices of peripheral neuropathy were also related to height in these analyses. Glycosylated hemoglobin was significantly related to thermal sensitivity and the peroneal and posterior tibial motor nerve-conduction velocities but not to vibratory sensitivity. These data indicate that height has a marked influence on quantitative sensory, nerve-conduction, and clinical indices of diabetic peripheral neuropathy.

Adult↗

Determinants of quantitative sensory testing in non-neuropathic individuals.

We have studied characteristics of subjects that could potentially influence quantitative sensory measurements in 156 non-neuropathic individuals. All subjects had measurements of vibration perception at the hallux and index finger with the vibration sensitivity tester and measurements of cool and warm perception at the hallux with the thermal sensitivity tester. Age, height, and skin temperature were all inversely related (P less than 0.05) to vibration sensitivity at the hallux, while age was inversely related (P less than 0.01) to vibration sensitivity at the index finger. In multiple regression analyses the significant associations persisted (P less than 0.01). Neither cigarette smoking nor the occasional use of alcohol were related to the quantitative sensory indices. These data indicate that age, height, and skin temperature should be considered in the assessment of vibration perception and that thermal sensitivity is relatively resistant to these factors.

Adult↗

Somatosensory evoked potential measurements in percutaneous fluid aspiration from intraspinal cystic lesions.

Two patients were evaluated with somatosensory evoked potentials (SSEPs) before and after CT-guided fluid aspiration from cystic intraspinal lesions. Our objective was to use the information and the clinical response to this procedure to determine the suitability of the patients for surgical intervention. In both patients, one with a pseudomeningocele and the other with a subarachnoid cyst, improvement in their symptoms corresponded to significant changes in their SSEPs. We believe this technique may be useful in selected cases when it is unclear whether cystic intraspinal fluid collections are responsible for the patient's symptoms. An increase in amplitude and/or decrease in latency of SSEPs, along with clinical improvement after fluid aspiration, may indicate the potential benefit of surgical intervention.

Aged↗