PubMed HealthSearch

Biomedical subjects

D R Hamilton

Publications and source records attributed to D R Hamilton.

14 recordsLinked to original sources

How can i avoid lyme disease? What to say to the patient who asks.

No magic bullet for eliminating or medical breakthrough for preventing Lyme disease can be seen on the horizon. This fast-growing pandemic, second only to acquired immunodeficiency syndrome in public interest and concern, will probably continue to increase in range and incidence for the foreseeable future. Ticks are notoriously difficult to thwart, but intelligent application of control measures may be effective. More important, commonsense safety measures offer personal protection to the degree that they are assiduously practiced.

Animals

Oesophageal varices due to idiopathic portal vein thrombosis: a new surgical approach.

Life-threatening bleeding oesophageal varices due to idiopathic portal vein thrombosis occurred in a five-year-old male. Diagnosis was made by endoscopy and ultrasonography and decompression of the portal system performed by splenorenal shunt using the end renal vein to side splenic vein. This avoided the difficult mobilization of the splenic vein from the pancreatic bed in the conventional distal splenorenal shunt.

Budd-Chiari Syndrome

Lyme disease. The hidden pandemic.

Physicians will recognize Lyme disease faster if they maintain a high index of suspicion in a young patient with arthritis accompanied by negative rheumatoid factor and antinuclear antibody in combination with cardiac conduction problems or lymphocytic meningitis. The Lyme spirochete (Borrelia burgdorferi) has notable sensitivity to tetracycline, penicillin, and erythromycin; therefore, proper and complete treatment of the disease, once it is identified, can be easily achieved. Finkel observed that Lyme disease manifests itself as a "great imitator," as do many disorders caused by a spirochete. The total impact of Lyme disease on public health will be known only when the disease is fully recognized, consistently reported, and adequately managed.

Adult

Childhood Kaposi's sarcoma in Papua New Guinea.

In the country of Papua New Guinea, with its diverse population of nearly 3 million people, some disease patterns have a strange similarity to those seen in tropical Africa. Kaposi's sarcoma is a condition which is commonly seen in adult males; childhood Kaposi's sarcoma is relatively uncommon. Six cases, all males, aged from 6 months to 12 years have been detected since 1978. The primary organ involvement included skin in four cases, oral cavity in one case and lymph node in one case. The varied clinico-pathological features are described. This is the first report of such cases from Papua New Guinea.

Child, Preschool

Abdominal compressions during CPR: hemodynamic effects of altering timing and force.

To determine the optimal method of applying abdominal compressions during cardiopulmonary resuscitation (CPR), 3 levels of pressure (25, 50, and 100 torr) were applied to the abdomen a) continuously and b) as 500 msec pulses at 10 different phases during the CPR cycle in 8 anesthetized dogs. Thoracic aortic (Ao) and right atrial (RA) pressures were measured and PAo-PRA was calculated as the coronary perfusion gradient. A pneumatic piston device provided external chest compression (60/min, 120 lbs, for 50% of the cycle) and ventilation (80% O2, 12/min, at 20cm, H2O). Another identical device provided abdominal compression (AC) via an air-filled bladder. High-pressure (100 torr) AC applied for 500 msec commencing 200 msec prior to chest compression demonstrated the best overall profile, raising mean aortic pressure 26 torr (P less than 0.001) and peak coronary perfusion gradient pressure 17 torr (P less than 0.02) from control values during standard CPR of 58 and 41 torr, respectively. We conclude that applying high-pressure, 500-msec pulses of AC 200 msec before chest compressions significantly improves CPR hemodynamics.

Abdomen