Biomedical subjects
Publications and source records attributed to D R Levin.
We report the first case of a lymphangioma arising from the wall of the bladder, protruding into the lumen on 1 side and invading the peritoneal cavity on the other side. The presenting sign was painless macroscopic hematuria that had occurred initially 2 months before hospitalization. Treatment consisted of partial cystectomy. A review of the literature failed to reveal a report of an identical case.
Explore the source record for details and available documents.
A case of identical twins with bilateral vesico-ureteral reflux is presented. This case supports the hypothesis that primary vesico-ureteral incompetence may be an inherited lesion. The importance of investigating close relatives, especially identical twins, is stressed.
Unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway in rats result in a massive dopamine (DA) denervation of the ipsilateral striatum. Such animals have proven extremely useful as a model for the study of Parkinson's disease, an idiopathic neurodegenerative disorder of humans. Extensive unilateral DA disruption leaves the rat relatively normal in motor behavior; however, the extent of the lesion can be documented by drug-induced rotational behavior. When given an injection of a dopamine agonist, such as apomorphine or D-amphetamine, a lesioned animal will manifest rotational behavior; the number of turns correlates with the degree of unilateral denervation. In order to identify, for various studies, large numbers of animals with specific levels of denervation, the necessity of an automated and reliable rotational counting system (rotometer) becomes obvious. We have developed such a device that allows up to 16 rats to be tested concurrently with one inexpensive computer. This system is more reliable than, and certainly preferable to, more tedious methods such as videotaping and subsequent manual analysis or various other mechanical systems. Plexiglass, formed into large bowls, serve as the rotometer chambers. We have designed a simple, inexpensive, and accurate counting head that can be manufactured from readily available parts and that is very sturdy and reliable. This, together with a thoracic harness, completes the rotometer assembly. The rotational data, from up to 16 separate channels, is collected by a single-chip microprocessor and sent on a serial line to an IBM-type or MacIntosh host computer. There, it is graphically displayed on line and subsequently saved to disk with a novel acquisition program.(ABSTRACT TRUNCATED AT 250 WORDS)
A retrospective analysis of fluoroscopy-assisted plantar fasciotomy/calcaneal exostectomy is presented. The study included 34 patients whose symptoms were all improved to some degree by the procedure. On a five-point scale, the average improvement of preoperative symptoms was 3.2. There were a total of eight complications. The time it took to return to normal activities and until the pain became less than preoperatively was found to be decreased when compared with traditional methods. This technique, using a single, plantar medial, small incision should be considered as an option in the treatment of recalcitrant plantar fasciitis/heel spur syndrome.