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Biomedical subjects

D R Lewis

Publications and source records attributed to D R Lewis.

54 records · Page 3Linked to original sources

Biliary obstruction secondary to hepatic artery aneurysm: cholangiographic appearance and diagnostic considerations.

We present 2 patients with biliary compression by hepatic artery aneurysms and, for the first time, a cholangiographic demonstration of this rare cause of extrahepatic obstruction. The clinical features of hepatic artery aneurysms and modalities available for their diagnosis are reviewed. The cholangiographic appearance of smooth, gradual tapering of the biliary tree, although nonspecific, is not typical of the more commonly encountered bile duct carcinoma and should alert the investigator to the possibility of this uncommon diagnosis. Angiography must still be considered the procedure of choice but is unlikely to be performed without the necessary index of suspicion, either on clinical or radiologic grounds.

Adult↗

Massive cerebral edema associated with fulminant hepatic failure in acetaminophen overdose: possible role of cranial decompression.

Cerebral edema may complicate the course of fulminant hepatic failure. Response to conventional therapy has been disappointing. We present a patient with fatal acetaminophen-induced fulminant hepatic failure, with signs and symptoms of cerebral edema, unresponsive to conventional medical therapy. Cranial decompression was carried out. A justification of the need for further evaluation of cranial decompression in such patients is presented.

Acetaminophen↗

Predicting the effect of livestock inputs of E. coli on microbiological compliance of bathing waters.

Three alternative approaches to predicting delivery of faecal indicators from livestock sources to surface water in the catchment of the River Irvine, Ayrshire, Scotland, are described. These are a soil transport model which assumes all E. coli are transported through the soil, a regression model using observed E. coli concentrations in surface waters, and a distributed catchment model (PAMIMO). Each of these is linked to a simple group of equations describing inputs of E. coli from livestock to land, transport and inactivation in the river Irvine and mixing and inactivation in the sea. The models predict E. coli content of bathing water for Irvine beach. The regression model gives the best predictions of bathing water quality. The low values predicted by the soil transport model suggests that preventing surface runoff of faecal indicators from livestock would provide an adequate solution to the problem of bathing water contamination.

Animals↗

Dopant materials used in the microelectronics industry.

Advances in microelectronics have transformed the occupational environment of the electronics industry. Large quantities of potentially hazardous materials are now in routine use as integrated circuit manufacturing becomes more complex and specialized. While the acute hazards associated with these dopant materials are clear, the subacute and chronic effects are less evident. Many of these elements are trace elements in humans and may play roles in health and disease in minute concentrations. Early detection and prevention of adverse health effects requires both astute medical surveillance, industrial hygiene, and safety engineering efforts to eliminate the sources of exposure to workers.

Antimony↗