Biomedical subjects

D Rădulescu

Publications and source records attributed to D Rădulescu.

95 records · Page 6Linked to original sources

PubMedDate not supplied

Giant congenital nevi. A clinical and histopathological study.

17 cases of giant congenital nevi were reported. The lesions were located on the scalp, on the back and on the shoulders. The histopathological study revealed two cellular types of giant nevus; nevus cell type and neuroid type. Two types of neuroid structures were observed in neuroid type: Verocay bodies and pseudo-Meissnerian corpuscles. The congenital nature of a benign nevus includes the presence of nevus cells, single or in nests within the follicular epithelium, eccrine ducts or glands. Essentially, all giant nevi show conspicuous nevic cell permeation not only of the reticular dermis but typically also of the subcutis and even the fascia.

Adolescent↗

PubMedDate not supplied

Extensive cutaneous lymphoma.

The case of a 35-years-old patient with a progressive and densely developed subcutaneous tumour comprising the whole right cervical and subcutaneous region is presented. The tumour was painless of pale brown and light red colour, with no adherence on the epidermis and subjacent muscles. The patient has no pathological symptoms. After the histopathological examination we found the dermal infiltration with small, round or oval hyperchromatic cells and the histoenzymological investigation revealed intense positive markers CLA and MB2 pleading for their leukocytic nature while L26 reaction attested the B-cell nature of these lymphocytes and the diagnosis of polymorphous centroblastic malignant lymphoma (K type Working Classification).

Adult↗

PubMedDate not supplied

Retroperitoneal malignant fibrous histiocytoma without histological atypias.

A case of a 36-year-old woman suspected of hepatic hydatid cyst with dyseptic symptoms, hepatomegalia, profound pains in the right hypochondrium is presented. During the operation a 15/12/17 cm well-incapsulated tumour is extirpated. The tumour stretched from the upper right renal pole behind the right hepatic lobe as far as the diaphragm and while sectioning it was grey and orange. Histopathologically we found a fibrous histiocytoma with zones of storiform fascicular pattern alternating with areas of histocytic cells with vacuolar-foamy cytoplasm, rich in lipids and without atypias or mitoses. We report the frequency, histological aspects of the fibrous histiocytomas as well as some particularities of their retroperitoneal location.

Adult↗

PubMedDate not supplied

Gastric malignant schwannoma.

One case of gastric malignant schwannoma is presented, the clinical diagnosis, the morphological particularities and the prognostication of this tumour are discussed. Personal observation. In December 1986, the patient H. R., of female sex, aged 27, was hospitalised in "The Second Medical Clinic" of "St. Spiridon Hospital" for epigastric pains accompanied by melena. After analysing the evolution of the disease, it resulted that the patient had been suffering from epigastric pains, which gave unfavourable prognosis after a symptomatic treatment for 10 years.

Adult↗

PubMedDate not supplied

[Acute non-lithiasic cholecystitis].

The authors present 7 cases of acute non-lithiasic cholecystitis, representing 1.5% of the total number of acute cholecystitis cases in their personal statistics. The determining factor of the acute inflammatory process of the gallbladder was represented in 6 of the cases by non-lithiasic obstruction of the cystic duct. In the last case there was acute segmental cholecystitis secondary to a gallbladder septum, probably of congenital origin. Clinical and anatomo-pathological aspects are discussed, of acute non-lithiasic cholecystites, the origin of which is located in the diverticular apparatus of the biliary pathways. From the therapeutical viewpoint cholecystectomy is the most indicated attitude in such cases.

Abscess↗