PubMed Health⌕ Search

Biomedical subjects

D Raahave

Publications and source records attributed to D Raahave.

At least 37 records · Page 2Linked to original sources
PubMed1986

The infective dose of aerobic and anaerobic bacteria in postoperative wound sepsis.

Surgery for perforated appendicitis was used to estimate the infective dose of aerobic and anaerobic bacteria in postoperative wound sepsis. The wound sepsis rates were 22.6% (7/31) after treatment with intravenous ampicillin sodium and metronidazole and 23.5% (8/34) after penicillin G sodium, streptomycin, and metronidazole, a nonsignificant difference. Intraoperative sampling by velvet pads demonstrated that the density of aerobes did not differ significantly from that of anaerobes, either on the surface of the appendix, in peritoneal exudate (aspirated), or in the wound before closure. The predominant pathogens were Escherichia coli and Bacteroides fragilis. In 15 patients who developed wound sepsis, the density of aerobes and anaerobes was significantly higher at all sampling sites than in 50 noninfected patients. The median infective dose of aerobes and anaerobes together was 4.6 X 10(5) colony forming units.cm-2 in the operative wound. There was a significantly high correlation between the densities of bacteria during operation and subsequent wound sepsis.

Adolescent↗
PubMed1986

The significance of digital subtraction angiography (DSA) before operative treatment of hypernephroma in a horseshoe kidney.

A case of hypernephroma in a horseshoe kidney is reported in a patient with total situs inversus organorum. The diagnostic procedures are discussed, and the significance of digital subtraction angiography for both diagnosis and treatment is emphasized, as the presentation of the arterial and venous supplies is of great value for guidance in the surgical intervention, particularly when congenital malformations are present.

Angiography↗
PubMed1985

Retroperitoneal perforation of duodenal ulcer.

Retroperitoneal perforation of a duodenal ulcer occurred in a 51 year female. The patient was seriously ill, but recovered after laparotomy with drainage of an abscess, closure of the duodenum and a gastro-jejunal anastomosis. The diagnosis is difficult to establish because of the anatomical relationships.

Abscess↗
PubMed1984

Gas gangrene of the omental bursa following acute pancreatitis.

Acute pancreatitis with necrosis was followed by infection with Clostridium perfringens and formation of gas in the omental bursa. This could be seen preoperatively on an abdominal roentgenogram and was verified at operation. The patient recovered after debridement, drainage and irrigation and antimicrobial therapy.

Acute Disease↗
PubMed1983

Stone in the ampulla vateri in a child. A case report.

In spite of classic symptoms of gallstones in a 9-year-old girl, operation was delayed for several years, apparently because surgeons and pediatricians do not readily consider the possibility of obstructive gallstones in young patients. The operative treatment is similar in children and adults.

Adolescent↗
PubMed1983

A vascular band to Meckel's diverticulum.

In a Meckel's diverticulum, heterotopic tissue, inflammation and a vascular band co-existed. The band originating from the superior mesenteric artery, was separated from the mesentery and represented a remnant of the vitelline artery.

Diverticulitis↗
PubMed1982

Velvet pad surface sampling of anaerobic and aerobic bacteria: an in vitro laboratory model.

Velvet pads have been evaluated in an experimental, laboratory model, simulating intraoperative sampling of Staphylococcus epidermis, Escherichia coli and Bacteroides fragilis. After sampling, the pad was placed in a transport medium and kept in an anaerobic atmosphere, before being shaken and rinsed, followed by anaerobic and aerobic culture. This technique permitted quantitatively high recoveries of the test bacteria. Velvet pad sampling could be a measure to determine the density of aerobic and anaerobic bacteria during operation in an effort to predict the risk of postoperative wound sepsis.

Bacteria↗
PubMed1981

High-dose penicillin to prevent postoperative wound sepsis after ileocolorectal operations.

Two hundred and twenty-two patients were admitted to a controlled trial to investigate the effect of penicillin on the prevention of postoperative wound infection after ileocolorectal operations. The study group was treated with 5 MIU of penicillin intravenously twice daily for 4 days, starting at operation, together with an intraincisional injection of penicillin at wound closure. The rate of wound infection was 11/93 (11.8%), compared with 15/92 (16.3%) in the control group, which was given a regimen of 2 MIU penicillin and 0.5 g streptomycin twice daily for 5 days; no difference existed between these sepsis rates (p less than 0.05). Measurements of the operation wounds per- and post-operatively showed a mean infected wound length of 7.3 +/- 4.0 cm, this being only one third of the original wound length, and no difference existed between the two treatment groups. A rate of partial wound infections of 1 in 10 seems acceptable after ileocolorectal operations, especially when achieved by penicillin therapy, which is inexpensive and free of serious risks.

Administration, Topical↗
PubMed1981

Whole gut irrigation with saline, tinidazole and colistin before colorectal operations.

To date, 27 patients scheduled for colorectal operations have had their bowels prepared the day before operation by whole gut irrigation with up to 151 of an electrolyte solution (14 patients), while the other 13 patients had infused in addition 0.51 of a solution containing 500 mg tinidazole and 1 MIU colistin. During the operation, samples were taken from the abdominal and perineal operation wounds and the colorectal mucosa by a velvet pad rinse technique, which involved transportation in a CO2-atmosphere and cultivation in an anaerobic cabinet. The number of anaerobic bacteria present in the colon was significantly lower after the use of antimicrobials, while there was no such difference with regard to aerobic bacteria. There were no differences between the two groups in preclosure bacterial densities of abdominal and perineal wounds. The total number of bacteria inoculated, the wound inoculum, was considerably lower after antimicrobial administration. There were no infections in the 13 patients treated with these antimicrobials, while 4 out of the 14 patients in the control group developed infections.

Adult↗
PubMed1981

Septic wound complications after whole bowel irrigation before colorectal operations.

Ninety-three patients for whom a colorectal operation was planned had their bowel prepared mechanically by orthograde irrigation. The tube was sited in the duodenum via the pylorus under X-ray and TV control. The procedure was discontinued in 2 patients (2%), 15 patients (16%) experienced nausea and vomiting, while 76 patients (82%) experienced no discomfort. The mean duration of the irrigation was 216 min (90-476 min) and the mean volume of fluid used 10.21 (5.0 -15.0 1). There were no significant differences between pre-irrigation and post-irrigation blood chemistry. Twenty-three patients developed postoperative abdominal wound sepsis (26.7%), 4 (4.7%) had an intraabdominal abscess; 9 out of 12 patients (75%) had perineal wound sepsis. Escherichia coli and Bacteroides were the dominant species cultured from colorectal mucosa during operation as well as from infected abdominal and perineal wounds. Although the irrigation technique seems to clean the bowel to a degree not previously seen, this in itself is no guarantee of avoiding post-operative wound sepsis after colorectal operations.

Adult↗