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Biomedical subjects

D Radochová

Publications and source records attributed to D Radochová.

At least 19 recordsLinked to original sources
PubMed1990

Erythrocyte superoxide dismutase activity in patients with pernicious anemia and chronic lymphocytic leukemia.

Superoxide dismutase activity was determined in the erythrocytes of healthy individuals and patients suffering from pernicious anemia, chronic lymphocytic leukemia and dyserythropoetic anemia type II. Enzyme activity was significantly decreased in the group of patients with chronic lymphocytic leukemia treated with cytostatic drugs. Most pronounced decreased occurred in erythrocytes of patients with dyserythropoetic anemia.

Aged↗
PubMed1989

[Eosinophilic leukemia].

On the example of a patients with eosinophil leukaemia, which at first was manifested as eosinophilia in the peripheral blood stream and bone marrow without involvement of other organs and only after three years acquired the character of malignant growth, the authors draw attention to difficulties in the differential diagnosis of hypereosinophil syndrome. At the same time the authors review briefly views on the origin of eosinophil leukaemia, morphological and cytogenetic findings considered useful as evidence of this rare type of leukaemia.

Adult↗
PubMed1982

Hairy-cell leukemia and toxoplasmosis.

Investigation for Toxoplasma gondii infection using complement fixation test and microprecipitation method in agar gel was performed in fifteen patients with clinically and morphologically typical hairy-cell leukemia. Positive complement fixation test was found in four patients. In three patients an initially high complement fixation titer or its considerable increase associated with positive microprecipitation in agar gel suggested a recent toxoplasmosis. The importance of search for Toxoplasma gondii infection in hairy-cell leukemia patients especially before splenectomy and the necessity of reinvestigation after splenectomy is stressed.

Adult↗
PubMed1980

Congenital dyserytropoietic anaemia, type II (HEMPAS) in three siblings.

These siblings of a Czech family aged 21, 19 and 6 years, respectively, with congenital dyserythropoietic anemia, type II, (HEMPAS) are reported. In two elder siblings ferrokinetic studies revealed a rapid plasma 59Fe clearance, markedly decreased erythrocyte incorporation and shortened 51Cr red-cell survival. Direct anti-globulin test was found positive in one of them. Further investigations revealed low values of blood plasma cholesterol, total lipids, beta-lipoproteins, beta-carotine and vitamin E and A as well as low values of the prothrombin complex. Liver biopsy demonstrated siderosis and disseminated intravascular coagulation in the liver in both patients. The possible reasons for these humoral aberrations are discussed.

Adolescent↗