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D Raistrick

Publications and source records attributed to D Raistrick.

30 records · Page 2Linked to original sources
PubMed1991

Methadone in saliva.

Explore the source record for details and available documents.

Chromatography, High Pressure Liquid↗
PubMed1991

Methadone concentrations in plasma and their relationship to drug dosage.

We have developed a sensitive HPLC method for measuring methadone in plasma and have used it to establish that there is a linear relationship between plasma concentration and methadone dose over the range of 3-100 mg of methadone per day in a group of 31 addicts. We found a good correlation between dose and plasma concentration (r = 0.89), with the plasma methadone concentration increasing by 0.263 mg/L for every milligram of methadone consumed per kilogram of body weight. Five patients had unexpected high or low concentrations; this finding is discussed.

Chromatography, High Pressure Liquid↗
PubMed1990

Development of a district training strategy.

This paper reiterates the need for training in addiction for primary care workers and proposes motivational and structural explanatory frameworks to further our understanding of the difficulties in recruitment of staff from the variety of occupational groups to substance misuse training. This analysis is applied to inform the design and delivery of training locally. The basic tenets of a district training strategy are derived from this analysis and the training strategy for the two Leeds District Health Authorities is described. The strategy is based upon identification of the specific occupational needs of each primary care worker group at each stage of their career, and upon the utilization of available resources to fulfil their training needs in the occupation specific context. The different occupational groups have different roles to play in the prevention and management of substance misuse and the specific skills required will be closely tied into their particular role and based upon pre-existing skills. The resources for and methods of implementing the strategy are described.

Alcoholism↗
PubMed1989

The homogeneity of the alcohol dependence syndrome: a factorial analysis of the SADD questionnaire.

The Severity of Alcohol Dependence Data (SADD) questionnaire was administered under different conditions to three groups of patients in Leeds, Derry and Omagh. The results were then factor analysed using both exploratory and confirmatory procedures. There was a consistent and strong first factor which suggests that with some small modifications the SADD is a unidimensional scale. The results are interpreted as providing further evidence for the homogeneity of the alcohol dependence syndrome.

Adult↗
PubMed1987

Phenomenology of intoxication with toluene-based adhesives and butane gas.

The phenomenology of solvent inhalation was investigated comparing a group of young people who misused toluene (n = 31) with a group misusing butane (n = 12). Marked changes of mental state were invariable. Most users reported elevation of mood and hallucinations but a rich variety of phenomena was elicited. Nearly one-quarter of subjects had the potentially dangerous delusion of believing they were able to fly or swim. In the toluene group thoughts were more likely to be slowed, time appeared to pass more quickly and tactile hallucinations were more commonly reported than in the butane group. Withdrawal phenomena and tolerance were also looked at.

Adhesives↗
PubMed1987

Patterns of use and related harm with toluene-based adhesives and butane gas.

The patterns of use and related harm of solvent inhalation were investigated in a group of young people who misused toluene (n = 31) and a group misusing butane (n = 12). The two groups were similar in terms of patterns of use and solvent related harm. The toluene users were more likely to sniff only in a group setting, probably because of the long duration of intoxication. The toluene group were more approving in their attitudes towards taking other drugs.

Adhesives↗
PubMed1986

Cognitive group therapy for wives of alcoholics--a pilot study.

This paper reports on the results of group therapy for the wives of alcoholics where the alcoholics themselves were offered no treatment. The reason for running such a group is based on the idea that wives might seek help before their husbands, might attend sessions regularly and by acquiring better knowledge of alcoholism and improving their use of coping strategies might favourably influence their husbands' behaviour. At 6-month follow-up it was evident that coping styles were learned quickly; the sessions also provided support and friendship. Attendance at the group induced change, though not always positive in all marriages. Suggestions for future work are discussed.

Adaptation, Psychological↗
PubMedDate not supplied

Use of 'very low-dose phenobarbital' to investigate compliance in patients on reducing doses of methadone (detoxification).

Incorporation of very low doses of phenobarbital into a methadone linctus has enabled us to monitor the compliance of 7 patients receiving a reducing dose of methadone (detoxification) for treatment for opioid addiction. By measuring both plasma phenobarbital and methadone we detected 4 patients who consumed extra illicitly obtained methadone during the detoxification regime. Treatment outcome was poor; 11 of the original 18 patients dropped out of treatment within 14 days and of those who remained, 4 patients relapsed and reabused illicit drugs and 2 returned to a fixed dose of methadone. Laboratory measurements were successfully used to detect poor methadone compliance.

Adult↗