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Biomedical subjects

D Ratner

Publications and source records attributed to D Ratner.

At least 19 recordsLinked to original sources

An interlocking auricular composite graft.

BACKGROUND: Full-thickness defects of the nasal alar rim are relatively common following Mohs micrographic surgery for the treatment of long-standing or recurrent skin tumors. Composite grafts provide an excellent cosmetic and functional alternative for the repair of such defects. OBJECTIVE: A useful technique of auricular composite graft placement for reconstruction of full-thickness nasal alar rim defects is described. METHODS: The cartilaginous portion of the graft is extended beyond the borders of the soft tissue defect so that two cartilaginous pegs frame the lateral aspects of the graft. These pegs are then inserted into pockets prepared within the alar tissue of both sides of the defect, such that the graft interlocks with its recipient bed. A series of diagrams as well as a set of photographs from a representative case are provided, along with accompanying commentary, so as to enable the surgeon to incorporate this technique easily into his/her practice. CONCLUSION: The interlocking auricular composite graft technique permits increased graft stability, with decreased shearing forces of the graft over its recipient bed, and a larger surface area for revascularization, resulting in an increased probability of graft survival. This technique provides an elegant single stage alternative to current reconstructive techniques for full-thickness nasal alar rim defects measuring less than 1.5 cm in diameter.

Bandages

Mohs' micrographic surgery: an overview.

Microscopic control of surgical margins has made Mohs' micrographic surgery an increasingly appealing option for patients with large, recurrent, or difficult-to-treat basal cell and squamous cell carcinomas who require precise and effective surgical management. Understanding the pre-, peri-, and postoperative considerations in Mohs' surgery will help dermatology nurses better prepare and educate patients who undergo this procedure.

Basal Cell Carcinoma

Basic suture materials and suturing techniques.

There is a need for surgeons to be able to make a logical decision regarding which suture materials to use in a given clinical situation because the choice of wound-closure materials may make a difference in wound healing and the ultimate functional and cosmetic result obtained. This article will review the basic physical, handling, and tissue-reaction characteristics of commonly used suture materials. Basic suturing techniques are also reviewed. Knowledge of multiple suturing techniques provides versatility, individuality, and optimal closure of surgical wounds.

Absorption

Merkel cell carcinoma.

Merkel cell carcinoma is a malignant neuroendocrine tumor with features of epithelial differentiation. Biologically aggressive, it may be difficult to diagnose and, particularly in its late stages, even more difficult to treat effectively. This article addresses what is known and what is still controversial about the histogenesis, diagnosis, and management of Merkel cell carcinoma and the structure and function of the Merkel cell from which it is believed to be derived. The incidence, clinical presentation and diagnosis, ultrastructure, immunocytochemistry, treatment, and prognosis of this tumor will be discussed.

Carcinoma, Merkel Cell

Soft tissue reconstruction with skin grafting.

Free skin grafts for soft tissue reconstruction can be classified into three types: full-thickness skin grafts, split-thickness skin grafts, and composite grafts. The indications, techniques, donor site considerations, and postoperative complications of each type of skin graft are reviewed.

Dermatologic Surgical Procedures

Vitamin B12 and folate levels in long-term vegans.

Serum vitamin B12, serum folate and red blood cell (RBC) folate levels were examined among 36 strict vegans of 5-35 years' duration. Vitamin B12 levels among the vegans were generally lower than in a control population. Most of the vegans had vitamin B12 values less than 200 pg/ml. RBC folate levels were normal but serum folate levels among the vegans were higher than among the controls. None of the vegans had any hematologic evidence of vitamin B12 deficiency, however four of them had neurologic complaints. Long-standing vegans should be monitored for vitamin B12 levels.

Adolescent

Seasonal variation in blood cholinesterase activity.

Blood cholinesterase activity was determined in 482 people to establish the range of enzyme values in residents of our area. A decrease in activity was noted during the summer, which recurred the following summer. This was due to a selective decrease in plasma pseudocholinesterase activity. The seasonal variation may be explained by the ingestion of pesticide residues found in fruit and vegetables.

Adolescent