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Biomedical subjects

D Reichelt

Publications and source records attributed to D Reichelt.

At least 37 records · Page 2Linked to original sources
PubMed1990

[The effect of vitamin E on the survival rate and biochemical parameters such as isocitrate dehydrogenase, lactate and selected peptidases and proteases during endotoxic shock in the rat].

Protective effect of the investigated alpha-tocopherol solution regarding survival and changes of several biochemical parameters in rat endotoxin shock could already be demonstrated after application of the solvent (special oil HCO-60) alone. An additional effect of Vitamin E was observed only in DP IV activity and leukocyte counts.

Animals↗
PubMed1987

[Experiences with bronchoalveolar lavage in disseminated and other lung diseases].

In 860 patients 980 bronchoalveolar lavages were performed. The repeated BAL allows conclusions of the effect of treatment and the prognosis of the disease. BAL is together with other clinical findings an important new method in pulmology. Its value in diagnosis of interstitial pulmonary diseases and other pulmonary diseases is described with special view to occupational expositions.

Alveolitis, Extrinsic Allergic↗
PubMed1984

Co-existence of immunoreactivity to anti-dopamine, anti-serotonin and anti-vasotocin in the cerebral giant neuron of the pond snail Lymnaea stagnalis.

Consecutive sections of certain neurons in the central ganglia of the pond snail Lymnaea stagnalis appear to be immunoreactive to anti-dopamine and anti-serotonin. The Cerebral Giant Neurons stain in addition with anti-vasotocin. The observations indicate the presence of two biogenic amines within the same neuron and in addition their co-existence with a biologically active peptide.

Animals↗
PubMed1980

Photoperiod-dependent neural control of the activity of the neurosecretory canopy cell in the lateral lobes of the cerebral ganglia of the freshwater pulmonate Lymnaea stagnalis (L.).

In the lateral lobes of the cerebral ganglia of the pulmonate freshwater snail Lymnaea stagnalis (L.) one large neurosecretory canopy cell (CC) and two droplet cells (DC) are present. With the ganglion-transplantation technique and with quantitative electron microscopy it is shown that photoperiodic stimuli control the neurosecretory activity of the CC via a stimulatory extrinsic neural pathway. The eyes do not play an important role in this regulatory process. The neurosecretory activity of the DC is not affected by differences in photoperiod. The significance of the photoperiodic control of CC activity is discussed in relation to the pathway for the endocrine control of reproduction which is known to be photoperiod-dependent.

Animals↗
PubMed1980

Immunocytochemical identification of neural elements in the central nervous systems of a snail, some insects, a fish, and a mammal with an antiserum to the molluscan cardio-excitatory tetrapeptide FMRF-amide.

With an antiserum to the molluscan cardio-excitatory tetrapeptide FMRF-amide neurons and/or nerve fibers were immunocytochemically identified in the central nervous systems of a snail (Lymnaea stagnalis), some insects (Leptinotarsa decemlineata, Periplaneta americana, Locusta migratoria, Pieris brassicae), a fish (Poecilia latipinna) and a mammal (mouse). The fact that immunoreactive material was observed in neurohaemal organs (corpora cardiaca of the insects) as well as in axon terminals ending on other neurons, seems to indicate that this peptide can function as a neurohormone and/or as a neurotransmitter. The results sustain the hypothesis that biologically active peptides have a wide distribution in the animal kingdom.

Animals↗
PubMed1980

[Laboratory staged-programme in diseases of the lung. Aspects and recommendation. (author's transl)].

The dynamic of biochemical processes opened recently an enlarged arsenal of new diagnostic possibilities for the physician. The exponential increase of scientific knowledge led to a progressive increase in the frequency of laboratory analyses. First the laboratories attempted to confront this development by means of rationalization of the structure, organization and analytic factors. Today the laboratories are confronted with a wide-spread polypragmasy, the demand of redundant parameters and irrelevant analyses increases. This contradiction can be solved only by a process of interdisciplinary responsibility. Very important is a change with the result of an improvement of the parameterpalettes leading to a rationalization of the diagnosis. Up to now there is a loch of systematical scientific investigations for the objectiveness and improvement of laboratory parameterpalettes concerning basis diagnosis, differential diagnosis and control of therapy effects in lung diseases. Obviously the cause for this problem in the structure and function of the organ "lung". In this special cases laboratory diagnosis possesses inbordinale relevance. As for the diagnostical process parameters of the function as well as X-ray diagnosis and morphological findings possesses priority. In this study an attempt is made to classify the diagnostically relevant parameters and to force them in a staged system of the medical supervision. With this conception the physician has the possibility to demand laboratory investigations on a scientifically founded basis.

Efficiency↗
PubMed1979

ACTH-like immunoreactivity in two electronically coupled giant neurons in the pond snail Lymnaea stagnalis.

Two giant neurons (diameter 130 micron) were identified immunocytochemically by means of the unlabeled antibody enzyme technique with anti-ACTH 1-39 and 1-24 in the pond snail Lymnaea stagnalis. The cells are located in the visceral and the right parietal ganglion, respectively. They contain moderately electron dense elementary granules (diameter 150-160 nm). By means of the intracellular horseradish peroxidase injection technique it was shown that the cells send fibres into the neuropiles of various ganglia and into nerves. Synapses occur on the fine fibre branches in the neuropile. Synapse-like structures were found on the cell bodies and on the major fibres. The giant neurons are electrotonically coupled. With toluidine blue staining for small peptides it was demonstrated that in the central nervous system of the pond snail numerous peptidergic neurons occur in addition to those identified with the classical staining methods for neurosecretion.

Adrenocorticotropic Hormone↗
PubMed1979

An ultrastructural study of the neurosecretory canopy cell of the pond snail Lymnaea stagnalis (L.), with the use of the horseradish peroxidase tracer technique.

The paired, electrotonically coupled neurosecretory Canopy Cells (CC) of the pond snail Lymnaea stagnalis were microiontophoretically injected with horseradish peroxidase (HRP). Whole mount preparations and ultrathin sections of injected CC were studied to describe in detail the morphology of the CC, their axon tracts and neurohaemal areas. The CC release their secretory product at three different sites, viz. from the soma and from axon terminals in the intercerebral commissure and in the median lip nerve. Neural control over the CC occurs by few synapses found exclusively on the CC axon, not on the cell body. One type of "en passant" synapse was identified. Two morphologically distinct types of synapselike structures (SLS) are numerous. The site of electrotonic coupling between the two CC is most probably located in the cerebral commissure. Serial sectioning showed that the axons contact each other over more than 130 micrometers. The contact is very intimate and the axon membranes interdigitate in a complex manner. Gap junctions, which are often described as the sites of electrotonic coupling, were not found.

Animals↗
PubMed1976

[Experimental coronary thrombosis in dogs. Morphologic investigations (author's transl)].

By means of electric induction without opening the chest in 23 dogs coronary thromboses were produced with the aid of a standardized method based on a test model of Salazar (1961). The morphological results are reported. 13 of the dogs showed coronary thromboses. At the same time in 12 animals a myocardial infarction could be registered. Altogether, we observed 17 myocardial infarctions. The electric field led to differently severe lesions in the walls of the coronary arteries. The significance of this test model is discussed.

Animals↗
PubMed1976

[Morphologic investigations on experimental coronary thromboses in pigs (author's transl)].

With the aid of a standardized method basing on a report of Salazar (1961) coronary thromboses in pigs were produced by means of electric induction without opening the chest. 12 of 13 pigs showed thromboses in coronary arteries, in 8 animals with embolization of the thrombotic material. At the sametime in 8 pigs a myocardial infarction could be registered. The significance of these experiments discussed.

Animals↗