Multiple blood samples without multiple sticks.
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Biomedical subjects
Publications and source records attributed to D Reker.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.
This paper reviews older results on EEG and behavioral effects of heroin and opiate antagonists in exaddicts, and presents new findings on the effects of naltrexone in men who have never been addicted. Ten normal volunteers were given on three separate occasions placebo, 50 mg or 100 mg of naltrexone. The average alpha frequency was significantly slower after naltrexone than after placebo. Naltrexone elicited a significant reduction of breathing rate and oral temperature. Those results indicate that naltrexone does not act as a pure narcotic antagonist in non-addicted men.
Spontaneously occurring mood states and various physiological indices were evaluated on three occasions in a group of eight healthy males. Results reveal that significant positive correlations exist among five of the six factors comprising the Profile of Mood States (POMS). This finding is related to previous research on the POMS and varied methodologies utilized in those reports. Reliable positive correlations of the POMS factors Depression and Tension with heart rate and diastolic blood pressure were obtained. The Anger factor of the POMS also correlated positively and significantly with heart rate. These findings are discussed in terms of the relationship between POMS factors and anxiety.