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Biomedical subjects

D Rickards

Publications and source records attributed to D Rickards.

26 records · Page 2Linked to original sources

A percutaneous perineal approach for cystoscopy in male dogs.

A percutaneous perineal approach is presented as a further technique for rigid cystoscopy in male dogs. The anatomy of the urethra in the male dog prevents rigid cystoscopy by non-surgical means but a fine flexible fibrescope may be used. Perineal urethrotomy and prepubic percutaneous puncture techniques using rigid endoscopes have been described; however, both have possible serious complications. This new procedure allows access for visual examination, biopsy and resection as necessary and appears to have few adverse sequelae.

Animals

Dehydration, antidiuretic hormone and the intravenous urogram.

The efficacy and safety of attempts to dehydrate patients before intravenous urography in order to improve image quality have been called into question by several authors. Antidiuretic hormone (ADH) assays described here show that dehydration of outpatients as typically practised by radiology departments does not affect plasma ADH levels. Furthermore, the very act of contrast-agent administration causes a rapid rise in plasma ADH concentration to levels higher than would in any case be expected from modest dehydration. Since the likely effect on circulating ADH of attempted dehydration is dwarfed by the physiological response to a contrast agent, it is considered that such efforts are entirely superfluous.

Body Water

The radiology of incontinence.

Incontinence is defined by the International Continence Society (Bates et al, 1979) as an involuntary loss of urine which can be objectively demonstrated and causes a social or hygienic problem. It is therefore both a symptom and a sign. Medical and surgical treatments are available and radiological investigation is helpful in many patients.

Adult

Pressure changes in the dilated upper urinary tract on perfusion at varying flow rates.

The conventional Whitaker test assesses the pressure response to a constant perfusion rate of 10 ml/min. Twenty-eight kidneys were perfused at increasing flow rates up to 20 ml/min. Nine became obstructed at rates of 12 to 20 ml/min. The feasibility of such a high urine output has been tested and confirmed. The standard Whitaker test may therefore miss some cases with potentially obstructive hydronephrosis, the effects of which may be deleterious to renal function.

Adolescent

Micturition disturbance in Parkinson's disease.

Ten men with longstanding idiopathic Parkinson's disease (IPD) were investigated by urodynamic and electromyographic methods. The urodynamic studies were repeated after stopping anti-Parkinsonian medication for several hours. All patients showed a difference between the two studies, but the changes were unpredictable. Three patients who had high residual urine volumes in both studies were thought to have prostatic obstruction. EMG analysis showed no evidence of a lower motor neurone lesion affecting the striated urethral sphincter. It was concluded that micturition difficulty in the patient with IPD is due to detrusor hyperreflexia, influenced by the basal ganglia, which is not associated with impaired striated urethral sphincter activity.

Adult