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Biomedical subjects

D Riley

Publications and source records attributed to D Riley.

At least 181 records · Page 10Linked to original sources
PubMed1987

Drink-driving and the alcohol beverage industry: will reducing per capita consumption solve the problem in the United Kingdom?

The impact of drinking and driving is one focus of the mounting concern in the West over the widespread incidence of alcohol-related problems. Conventional wisdom, in the United Kingdom as well as in other countries, suggests that reducing average consumption levels will diminish the impact of the negative effects of alcohol including drinking and driving. But whether policies designed to achieve changes in per capita consumption by increasing alcohol taxes across the board constitute the most effective strategy to reduce drinking and driving is called into question. A number of competing interventions directed at the alcohol beverage industry are analysed and new directions for producers and policymakers are proposed.

Adolescent↗
PubMed1987

Hepatic estrogen receptor in the turtle, Chrysemys picta: partial characterization, seasonal changes and pituitary dependence.

A hepatic estrogen receptor is described from female turtles, Chrysemys picta. The receptor adheres to DNA after incubation with [3H]estradiol and can be eluted with a linear salt gradient as a single component with an elution maximum of 0.21 M. It is steroid-specific, binding estrogens, but not androgens or progestins. Specific binding saturates between 3 and 7 nM [3H]estradiol-17 beta and Scatchard analysis gave a Kd of 2 X 10(-9) M and a maximal binding capacity of 3.02 fmol/mg protein. Hypophysectomy reduces hepatic estradiol receptor from 70 fmol/g tissue in control animals to non-detectable levels. Growth hormone replacement partially restored the receptor to 36% of control. Significant changes in receptor occur during the ovarian cycle.

Animals↗
PubMed1986

Social ties: subgroup differences in costs and benefits.

Social ties can be stressful as well as supportive. Are these opposing effects linked, and can they help explain subgroup differences in the efficacy of social support? These questions were applied to data on social support in response to stressful life events. The subjects were 314 women randomly chosen from the registration list of a neighborhood health center in Boston. The data were from the initial interviews of a larger study. The findings include the following: The mobilization of social support was associated with better psychological well-being for women with greater personal resources, but not for those with lower levels of personal resources. Women with lower levels of personal resources were more distressed by life events in the lives of their significant others, especially as the number of these events increased. The subgroup effects of interpersonal support and stress on psychological well-being were independent, separate effects. In sum, women with greater material and psychological resources derived more beneficial support and suffered less stress from their social ties.

Adaptation, Psychological↗
PubMed1985

Analysis of inactive X chromosome structure by in situ nick translation.

Nick translation assays of fixed interphase female fibroblasts with tritiated nucleotides demonstrated a characteristic absence of label over sex chromatin. The chromatin bodies were nearly always peripheral in location and a ribbon of nick translatable DNA was detected between the sex chromatin and the nuclear envelope. High voltage electron microscopy indicated the possibility of a special nuclear envelope attachment region. The apparent resistance of sex chromatin to nick translation did not appear to be due to resistance to DNase I attack.

Cells, Cultured↗