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Biomedical subjects

D Romero Alvira

Publications and source records attributed to D Romero Alvira.

15 recordsLinked to original sources
PubMed1995

[Oxidative stress and infectious pathology].

Pathogenic organism can be considered as pro-oxidant agents because they produce cell death and tissue damage. In addition organism can be eliminated by specific cell defense mechanism which utilize in part, reactive oxygen radicals formed by oxidative stress responses. The cause of the necessarily defense process results in cell damage thereby leading to development of inflammation, a characteristic oxidative stress situation. This fact shows the duality of oxidative stress in infections and inflammation: oxygen free radicals protect against microorganism attack and can produce tissue damage during this protection to trigger inflammation. Iron, a transition metal which participates generating oxygen free radicals, displays also this duality in infection. We suggest also that different infectious pathologies, such as sickle cell anemia/malaria and AIDS, may display in part this duality. In addition, it should be noted that oxidative damage observed in infectious diseases is mostly due the inflammatory response than to the oxidative potential of the pathogenic agent, this last point is exemplified in cases of respiratory distress and in glomerulonephritis. This review analyzes these controversial facts of infectious pathology in relation with oxidative stress.

Acquired Immunodeficiency Syndrome↗
PubMed1992

[Dietary intake patterns in the school health program].

AIM: To investigate dietary intake patterns among school-students. DESIGN: An observational prospective study. A dietary survey was used to establish how many times habitual foods were eaten each week. SITE. The population of the northern half of the city of Soria. (North Soria Health Centre). PARTICIPANTS: All the school-children aged 6 and 7 (74 boys and 57 girls in both the private and public sectors) took part in the programme. MEASUREMENTS AND MAIN FINDINGS: The intake of foodstuffs was stratified as greatest in quartiles. The consumers of sweet "junk" foods also ate significantly more savory "junk" food (p = 0.00009). We found and inverse consumption relationship between savory "junk" foods and an intake of greens and root-crops (p = 0.03) and of pasta and rice (p = 0.008). The lower consumption of greens and fruits was linked to a lower consumption of fish (p = 0.023), to a lower consumption of meat (p = 0.037) and of meat products (p = 0.008). Lower consumption of eggs was linked to a greater consumption of meat (p = 0.016) and fish (p = 0.029). CONCLUSIONS: The consumption of savory "junk" foods and meat products can replace nutrients of a high biological value which are found in greens and root-crops. New studies to deepen the taxonomical analysis of the school diet are required. These should identify eating patterns which could endanger health in adult life.

Chi-Square Distribution↗
PubMed1991

[Cardiac diseases related to free radicals and active oxygen species. Pro-oxidation and anti-oxidation in cardiology (part 2)].

In this second part, we study in detail the most important cardiological diseases showing the physiopathological consideration to support the importance of the stationary equilibrium between pro-oxidation and anti-oxidation to maintain the cardiovascular health. Ischemic cardiopathy and its risk factors (lipids, smoke, blood hypertension, alcohol, etc.), anti-oxidation, different cardiac diseases (coronary insufficiency, blood hypertension, congestive heart insufficiency, cardiomyopathies), are analyzed, and finally, we make clear certain information related to the onset of nitrites tolerance phenomenon and its treatment with anti-oxidation products.

Animals↗
PubMed1991

[Ambulatory aerosol therapy in the treatment of chronic pathology of the O.R.L. region].

This study considers the efficacity of the ambulatory aerosol therapy in chronic cases of the ENT area. A nebulizer, air-jet type, of 4 microns MMAD, was the device employed, and an ample spectre antibiotic (cefotaxime) a mucolytic (N-acetyl-cysteine) plus a corticoid (methyl-prednisolone) the associated drugs. The antibiotic was discarded when otitis were the problem. The results have been favourable in 75 percent of the cases whilst negative in the resting 24 percent of the treated subjects.

Acetylcysteine↗
PubMed1991

[Cardiac diseases related to free radicals and active species of oxygen. Biochemistry (1)].

In the first part of this paper, a group of definitions are explained in order to understand the mechanisms groups of the most important enzymes which participate in the formations of free radicals and active species of oxygen in the heart. Furthermore, we focus on chemistry and the production of these different active species of oxygen, rounding of by giving information related to the importance of hypoxia-reoxygenation, as well as the lipidic peroxidation in the formation of oxygen free radicals. All this information provides us with a biochemical baseline to write a second part about the cardiovascular pathology related to the lack of equilibrium between pro-oxidation and anti-oxidation.

Biochemical Phenomena↗