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Biomedical subjects

D S Bhandarkar

Publications and source records attributed to D S Bhandarkar.

At least 19 recordsLinked to original sources
PubMed1999

Spray of phospholipid powder reduces peritoneal adhesions in rabbits.

BACKGROUND: The possible effects of peritoneal dialysis and a combination of two exogenous phospholipids, dipalmitoylphosphatidylcholine (DPPC) and phosphatidylglycerol (PG), on experimentally induced intraperitoneal adhesion formation in rabbits were compared. METHODS: Fifty New Zealand rabbits equally divided in five groups underwent a midline laparotomy to create a right iliac fossa 5 x 1 cm parietal peritoneal defect and a matching defect over the adjacent large bowel. In 10 control rabbits (group I) the abdominal wound was closed without any further intervention. Twenty rabbits forming groups II and III underwent two sessions of peritoneal dialysis, one following abdominal closure and the second 24 h later, through a catheter placed at surgery. Rabbits in group III received an intraperitoneal injection of DPPC and PG after each session of dialysis. In 10 animals (group IV) a DPPC gel was applied to the defect over the large bowel and in 10 animals (group V) the peritoneal cavity was sprayed with a 'puff of DPPC:PG (7:3) powder prior to abdominal closure. All the animals were killed a week after the laparotomy to assess the extent of adhesion formation. RESULTS: The formation of adhesions was reduced in all the groups compared to the controls but a statistically significant difference was observed only in the group receiving the intraperitoneal 'puff' of DPPC:PG powder. CONCLUSION: A combination of DPPC and PG sprayed as a 'puff' intraperitoneally reduces experimentally induced peritoneal adhesions in rabbits.

1,2-Dipalmitoylphosphatidylcholine↗
PubMed1993

Benign cystic peritoneal mesothelioma.

The well defined but rare entity of benign cystic mesothelioma is reported. The aetiology of this neoplasm remains obscure. The presenting features make a precise preoperative diagnosis difficult; information provided by computed tomography and cytology may help. A firm diagnosis can only come from electron microscopic or immunohistochemical examination of the tumour. Diagnostic accuracy and diligent follow up are essential because, although the tumour is considered benign, it does tend towards local recurrence.

Cysts↗
PubMed1993

Carcinoma of the breast at the site of migrated pacemaker generators.

We report two patients in whom breast malignancy developed in the proximity of 'migrated' pacemaker generators. These cases and the similar ones reported in the literature raise concerns whether this association is merely coincidental or whether the pacemaker generator is responsible for the occurrence in some inexplicable manner. We urge for a routine, careful examination in all patients with implanted pacemaker generators at follow-up visits. This would help in (a) timely detection of migration of the pacemaker generators and (b) earlier diagnosis of any mass developing close to the migrated generators.

Aged↗
PubMed1990

Opponensplasty--an experience of twenty-three cases using three techniques.

Twenty-three opponensplasties were performed in 21 subjects. Flexor sublimis transfer was carried out in 15 hands, brachioradialis transfer in 4 hands, Makin's translocation of flexor pollicis longus in 2 hands and our modification of Makin's procedure in 2. The results were graded as excellent in 13 hands, good in 6 hands, fair in 3 hands and poor in 1 hand. Further, the power of pinch was graded as good in 14 hands, fair in 7 hands and poor in 2 hands. We suggest that it is almost always possible to devise an appropriate procedure to restore the opposition of the thumb.

Adolescent↗
PubMedDate not supplied

Laparoscopic cholecystectomy in India.

The first 100 cases of laparoscopic cholecystectomy carried out in a "developing country" are studied. There were 77 females and 23 males. The mean age was 48 years (24-82 years). There was no mortality and 2% morbidity. The mean operative time was two hours and 15 minutes in the first 50 cases, one hour and 50 minutes in the subsequent 50. Twelve cases were converted to open surgery, nine within the first 50 cases, three in the subsequent 50. In developing countries the challenge of financial constraints as also a different spectrum of abdominal pathology calls for greater efforts of innovation and improvization. However, the rewards of laparoscopic cholecystectomy as compared to open cholecystectomy are significant in developing countries in terms of shorter hospitalisation (3.6 vs. 13 days), early return to work (12 vs. 36 days), better hospital bed utilization, and reduced expense.

Adult↗