Paraneoplastic syndromes in metastatic disease.
OBJECTIVES: To provide an overview of selected paraneoplastic syndromes associated with metastatic disease with potential life-threatening implications, and the nursing implications of each. DATA SOURCES: Published articles and book chapters related to paraneoplastic syndromes in metastatic disease. CONCLUSIONS: Paraneoplastic syndromes in metastatic disease are associated with various primary tumors and can affect many organ systems. Early recognition and management can minimize the potential life-threatening effects of the syndromes. IMPLICATIONS FOR NURSING PRACTICE: Oncology nurses need to be aware of the potential for paraneoplastic syndromes that can compromise a patient's health status. Appropriate assessment and intervention of paraneoplastic syndromes can have a positive impact on patient outcomes and quality of life.